Oligomeric ethylene glycols as sorting tags for parallel and combinatorial mixture synthesis

Date

2005-03-14

Author

Wilcox, CS
Türkyılmaz, Serhan

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Sorting tags for chromatography allow mixtures of substrates to be carried through parallel chemical processes and then separated. The first sorting tags were fluorocarbons. An enabling characteristic of fluorous sorting tags is the predictable incremental increase in retention time with increasing fluorocarbon chain length. Here we describe a general approach to sorting tags and report our discovery of a second class of chromatographic tags. The new tags are oligomeric ethylene glycol (OEG) derivatives.

Subject Keywords

Organic Chemistry, Biochemistry, Drug Discovery

URI

https://hdl.handle.net/11511/42386

Journal

TETRAHEDRON LETTERS

DOI

https://doi.org/10.1016/j.tetlet.2005.01.109

Collections

Department of Chemistry, Article

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Citation Formats

C. Wilcox and S. Türkyılmaz, “Oligomeric ethylene glycols as sorting tags for parallel and combinatorial mixture synthesis,” TETRAHEDRON LETTERS, pp. 1827–1829, 2005, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/42386.