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Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population
Date
2009-12-01
Author
Demirdogen, Birsen Can
Demirkaya, Seref
Turkanoglu, Aysun
Bek, Semai
Arinc, Emel
Adalı, Orhan
Metadata
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This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Background Paraoxonase 1 (PON1) is protective against the development of atherosclerosis. a risk factor for ischemic stroke. PON1 gene has one promoter region (-107T/C) and two coding region (192Q/R and 55L/M) polymorphisms that affect the levels and catalytic efficiency of the enzyme. respectively. In this study. we aimed to determine the importance of -107T/C. 192Q/R and 55L/M polymorphisms of PON1 gene and three PON1 activity (diazoxonase, paraoxonase, arylesterase) as risk factors for ischemic stroke
Subject Keywords
Clinical Biochemistry
,
Cell Biology
,
Biochemistry
,
General Medicine
URI
https://hdl.handle.net/11511/42870
Journal
CELL BIOCHEMISTRY AND FUNCTION
DOI
https://doi.org/10.1002/cbf.1607
Collections
Department of Biology, Article