Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population

2009-12-01
Demirdogen, Birsen Can
Demirkaya, Seref
Turkanoglu, Aysun
Bek, Semai
Arinc, Emel
Adalı, Orhan
Background Paraoxonase 1 (PON1) is protective against the development of atherosclerosis. a risk factor for ischemic stroke. PON1 gene has one promoter region (-107T/C) and two coding region (192Q/R and 55L/M) polymorphisms that affect the levels and catalytic efficiency of the enzyme. respectively. In this study. we aimed to determine the importance of -107T/C. 192Q/R and 55L/M polymorphisms of PON1 gene and three PON1 activity (diazoxonase, paraoxonase, arylesterase) as risk factors for ischemic stroke

Citation Formats
B. C. Demirdogen, S. Demirkaya, A. Turkanoglu, S. Bek, E. Arinc, and O. Adalı, “Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population,” CELL BIOCHEMISTRY AND FUNCTION, vol. 27, no. 8, pp. 558–567, 2009, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/42870.