Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population

Date

2009-12-01

Author

Demirdogen, Birsen Can
Demirkaya, Seref
Turkanoglu, Aysun
Bek, Semai
Arinc, Emel
Adalı, Orhan

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Background Paraoxonase 1 (PON1) is protective against the development of atherosclerosis. a risk factor for ischemic stroke. PON1 gene has one promoter region (-107T/C) and two coding region (192Q/R and 55L/M) polymorphisms that affect the levels and catalytic efficiency of the enzyme. respectively. In this study. we aimed to determine the importance of -107T/C. 192Q/R and 55L/M polymorphisms of PON1 gene and three PON1 activity (diazoxonase, paraoxonase, arylesterase) as risk factors for ischemic stroke

Subject Keywords

Clinical Biochemistry, Cell Biology, Biochemistry, General Medicine

URI

https://hdl.handle.net/11511/42870

Journal

CELL BIOCHEMISTRY AND FUNCTION

DOI

https://doi.org/10.1002/cbf.1607

Collections

Department of Biology, Article

Citation Formats

B. C. Demirdogen, S. Demirkaya, A. Turkanoglu, S. Bek, E. Arinc, and O. Adalı, “Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population,” CELL BIOCHEMISTRY AND FUNCTION, vol. 27, no. 8, pp. 558–567, 2009, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/42870.