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Relationship of adipokines (adiponectin, resistin and RBP4) with metabolic syndrome components in pubertal obese children
Date
2013-06-01
Author
Boyraz, Mehmet
Cekmez, Ferhat
Karaoglu, Abdulbaki
CİNAZ, PEYAMİ
Durak, Mustafa
BİDECİ, AYSUN
Metadata
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Aim: To investigate the relationship between serum adiponectin, resistin and RBP4 levels and the components of metabolic syndrome. Patients & methods: Serum adiponectin, resistin and RBP4 levels were detected and analyzed in 148 8-18-year-old Turkish obese pubertal children with/without metabolic syndrome. Results: Adiponectin and resistin concentrations were significantly inversely correlated with BMI standard deviation score, homeostatic model assessment insulin resistance, waist circumference, triglyceride levels and diastolic and systolic blood pressure, and were directly correlated with high-density lipoprotein cholesterol. RBP4 concentrations were directly correlated with homeostatic model assessment insulin resistance, waist circumference, triglyceride levels and diastolic and systolic blood pressure, and inversely correlated with high-density lipoprotein cholesterol. Conclusion: Adiponectin, RBP4 and, in particular, resistin levels may be used as suitable predictive biomarkers of metabolic syndrome.
Subject Keywords
Clinical Biochemistry
,
Drug Discovery
,
Biochemistry, medical
URI
https://hdl.handle.net/11511/68308
Journal
BIOMARKERS IN MEDICINE
DOI
https://doi.org/10.2217/bmm.13.14
Collections
Graduate School of Natural and Applied Sciences, Article
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M. Boyraz, F. Cekmez, A. Karaoglu, P. CİNAZ, M. Durak, and A. BİDECİ, “Relationship of adipokines (adiponectin, resistin and RBP4) with metabolic syndrome components in pubertal obese children,”
BIOMARKERS IN MEDICINE
, pp. 423–428, 2013, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/68308.