Relationship of adipokines (adiponectin, resistin and RBP4) with metabolic syndrome components in pubertal obese children

Date

2013-06-01

Author

Boyraz, Mehmet
Cekmez, Ferhat
Karaoglu, Abdulbaki
CİNAZ, PEYAMİ
Durak, Mustafa
BİDECİ, AYSUN

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Aim: To investigate the relationship between serum adiponectin, resistin and RBP4 levels and the components of metabolic syndrome. Patients & methods: Serum adiponectin, resistin and RBP4 levels were detected and analyzed in 148 8-18-year-old Turkish obese pubertal children with/without metabolic syndrome. Results: Adiponectin and resistin concentrations were significantly inversely correlated with BMI standard deviation score, homeostatic model assessment insulin resistance, waist circumference, triglyceride levels and diastolic and systolic blood pressure, and were directly correlated with high-density lipoprotein cholesterol. RBP4 concentrations were directly correlated with homeostatic model assessment insulin resistance, waist circumference, triglyceride levels and diastolic and systolic blood pressure, and inversely correlated with high-density lipoprotein cholesterol. Conclusion: Adiponectin, RBP4 and, in particular, resistin levels may be used as suitable predictive biomarkers of metabolic syndrome.

Subject Keywords

Clinical Biochemistry, Drug Discovery, Biochemistry, medical

URI

https://hdl.handle.net/11511/68308

Journal

BIOMARKERS IN MEDICINE

DOI

https://doi.org/10.2217/bmm.13.14

Collections

Graduate School of Natural and Applied Sciences, Article

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Citation Formats

M. Boyraz, F. Cekmez, A. Karaoglu, P. CİNAZ, M. Durak, and A. BİDECİ, “Relationship of adipokines (adiponectin, resistin and RBP4) with metabolic syndrome components in pubertal obese children,” BIOMARKERS IN MEDICINE, pp. 423–428, 2013, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/68308.