Show/Hide Menu
Hide/Show Apps
anonymousUser
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Açık Bilim Politikası
Açık Bilim Politikası
Frequently Asked Questions
Frequently Asked Questions
Browse
Browse
By Issue Date
By Issue Date
Authors
Authors
Titles
Titles
Subjects
Subjects
Communities & Collections
Communities & Collections
Use of Nanoparticles in Tissue Engineering and Regenerative Medicine
Download
10.3389fbioe.2019.00113.pdf
Date
2019-05-24
Author
Fathi-Achachelouei, Milad
Knopf-Marques, Helena
Ribeiro da Silva, Cristiane Evelise
Barthes, Julien
Bat, Erhan
Tezcaner, Ayşen
Vrana, Nihal Engin
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
8
views
0
downloads
Advances in nanoparticle (NP) production and demand for control over nanoscale systems have had significant impact on tissue engineering and regenerative medicine (TERM). NPs with low toxicity, contrasting agent properties, tailorable characteristics, targeted/stimuli-response delivery potential, and precise control over behavior (via external stimuli such as magnetic fields) have made it possible their use for improving engineered tissues and overcoming obstacles in TERM. Functional tissue and organ replacements require a high degree of spatial and temporal control over the biological events and also their real-time monitoring. Presentation and local delivery of bioactive (growth factors, chemokines, inhibitors, cytokines, genes etc.) and contrast agents in a controlled manner are important implements to exert control over and monitor the engineered tissues. This need resulted in utilization of NP based systems in tissue engineering scaffolds for delivery of multiple growth factors, for providing contrast for imaging and also for controlling properties of the scaffolds. Depending on the application, materials, as polymers, metals, ceramics and their different composites can be utilized for production of NPs. In this review, we will cover the use of NP systems in TERM and also provide an outlook for future potential use of such systems.
Subject Keywords
Tissue engineering
,
Regenerative medicine
,
Metallic nanoparticles
,
Ceramic nanoparticles
,
Polymeric nanoparticles
,
Nanoparticles in bioinks
URI
https://hdl.handle.net/11511/43071
Journal
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
DOI
https://doi.org/10.3389/fbioe.2019.00113
Collections
Department of Chemical Engineering, Article