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A facile synthesis of (+/-)-mintlactone

1997-01-01
Tanyeli, Cihangir
ÇALİŞKAN, ZERRİN
Demir, AS
(+/-)-Mintlactone has been synthesized by applying a novel effective synthetic sequence. 4-Methylcyclohexanone was subjected to acetoxylation with Pb(OAc)(4). Hydrolysis followed by reaction with 2-chloroprogionyl chloride,then treatment with triethyl phosphite and, finally, Horner-Emmons-type intramolecular cyclization afforded (+/-)-Mintlactone.