Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study

Download

10.115520184152543.pdf

Date

2018-01-01

Author

BOZKURT, CELAL
ŞENKÖYLÜ, ALPASLAN
Aktas, Erdem
SARIKAYA, BARAN
SİPAHİOĞLU, SERKAN
Gürbüz, Rıza
Timucin, Muharrem

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

76
views

48
downloads

Objectives. Cage design and material properties play a crucial role in the long-term results, since interbody fusions using intervertebral cages have become one of the basic procedures in spinal surgery. Our aim is to design a novel Apatite-Wollastonite interbody fusion cage and evaluate its biomechanical behavior in silico in a segmental spinal model. Materials and Methods. Mechanical properties for the Apatite-Wollastonite bioceramic cages were obtained by fitting finite element results to the experimental compression behavior of a cage prototype. The prototype was made from hydroxyapatite, pseudowollastonite, and frit by sintering. The elasticmodulus of thematerial was found to be 32 GPa. Three intact lumbar vertebral segments were modelled with the ANSYS 12.0.1 software and this model was modified to simulate a Posterior Lumbar Interbody Fusion. Four cage designs in different geometries were analyzed in silico under axial loading, flexion, extension, and lateral bending. Results. The K2 design had the best overall biomechanical performance for the loads considered. Maximumcage stress recorded was 36.7MPa in compression after a flexion load, which was within the biomechanical limits of the cage. Conclusion. Biomechanical analyses suggest that K2 bioceramic cage is an optimal design and reveals essential material properties for a stable interbody fusion.

Subject Keywords

BONE, BONE, DIFFERENTIATION, HYDROXYAPATITE, CELLS

URI

https://hdl.handle.net/11511/46622

Journal

BIOMED RESEARCH INTERNATIONAL

DOI

https://doi.org/10.1155/2018/4152543

Collections

Department of Metallurgical and Materials Engineering, Article

Suggestions

OpenMETU
Core

Linear regression modeling to compare fluoride release profiles of various restorative materials Can-Karabulut, Deniz C.; Batmaz, İnci; SOLAK, HİKMET; Tastekinl, Mustafa (Elsevier BV, 2007-09-01) Objectives. The aim of this study was to compare the released fluoride profiles of various restorative materials by using linear regression analysis.
Response of peripheral blood mononuclear cells from lupus patients to stimulation by CpG oligodeoxynucleotides. Zeuner, RA; Klinman, DM; Illei, G; Yarboro, C; Ishii, KJ; Gürsel, Mayda; Verthelyi, D (2003-04-01) Objectives. Increased levels of hypomethylated CpG-containing DNA in sera from patients with systemic lupus erythematosus (SLE) may contribute to the initiation anduor perpetuation of the disease. This study characterizes the in vitro response of peripheral blood mononuclear cells (PBMC) from SLE patients to CpG DNA. Methods. Secretion of cytokines and IgM, cell proliferation and up-regulation of co-stimulatory molecules were evaluated in PBMC from SLE patients (n=24) and normal controls (n=24) after stimul...
Relationships Between Epidemiological Features and Tumor Characteristics of Breast Cancer Dogan, Lutfi; Kalaylioglu, Zeynep; Karaman, Niyazi; Ozaslan, Cihangir; Atalay, Can; Altinok, Mehmet (2011-01-01) Objectives. Breast cancer is a histological, morphological and molecular heterogenous disease. Like clinical outcomes and prognoses of different subtypes, etiologies might also be different. Therefore, epidemiologic risk factors like sociologic, demographic, antropometric, reproductive, and menstrual factors can be considered as an entity reflected in tumor features. This study was planned to explore the relation between well known risk factors of breast cancer and histological and molecular features of the...
Long-term results of arthrocentesis in degenerative temporomandibular disorders Oender, M. Ercuement; Tuez, Hakan H.; Kocyigit, Doruk; KİŞNİŞCİ, REHA ŞÜKRÜ (Elsevier BV, 2009-01-01) Objectives. Long-term efficacy of arthrocentesis was investigated in patients with degenerative temporomandibular disorder (TMD) in this clinical study.
Psychosocial issues of the Syrian Refugee College Students in Turkey Erdur Baker, Özgür; Özmen, Onur (2017-07-14) Objectives 1. Identify the institutional pressures ethnic minorities experience in a Chinese dominant society 2. Evaluate the coping strategies used in developing resilience 3. Develop a theoretical framework that can explain high levels of self-efficacy and its effects on marginalised groups Method Interviews were conducted with a sample of Hong Kong ethnic minority youth (n=20). The data were coded in multiple ways to enable comparisons, develop connections between different codes and validate the emergin...

Citation Formats

C. BOZKURT et al., “Biomechanical Evaluation of a Novel Apatite-Wollastonite Ceramic Cage Design for Lumbar Interbody Fusion: A Finite Element Model Study,” BIOMED RESEARCH INTERNATIONAL, pp. 0–0, 2018, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/46622.