CHANGES IN PATTERNS OF ALKALINE SERINE PROTEASE AND BACILYSIN FORMATION CAUSED BY COMMON EFFECTORS OF SPORULATION IN BACILLUS-SUBTILIS-168

Date

1992-03-01

Author

BASALP, A
Özcengiz, Gülay
ALAEDDINOGLU, NG

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Bacilysin biosynthesis and alkaline serine protease production in Bacillus subtilis 168 were monitored and compared in batch cultures when various effectors of sporulation were added at different stages of growth in a medium containing sucrose and glutamate. Depending on the time of addition, glucose affected sporulation and serine protease formation to the same extent, but had no effect on bacilysin production. Ammonium and L-alanine additions suppressed all three processes. Casamino acids severely interfered with bacilysin formation and sporulation, but not with protease formation. Decoyinine, a well-known inducer of sporulation, induced protease formation as well, but did not affect bacilysin biosynthesis. The extent of the observed effects depended largely on the time of metabolite additions. The results are discussed with reference to a possible coregulation of sporulation and the formation of bacilysin and alkaline serine protease in B. subtilis.

Subject Keywords

Applied Microbiology and Biotechnology, Microbiology, General Medicine

URI

https://hdl.handle.net/11511/47470

Journal

CURRENT MICROBIOLOGY

DOI

https://doi.org/10.1007/bf01568977

Collections

Department of Biology, Article

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Citation Formats

A. BASALP, G. Özcengiz, and N. ALAEDDINOGLU, “CHANGES IN PATTERNS OF ALKALINE SERINE PROTEASE AND BACILYSIN FORMATION CAUSED BY COMMON EFFECTORS OF SPORULATION IN BACILLUS-SUBTILIS-168,” CURRENT MICROBIOLOGY, pp. 129–135, 1992, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/47470.