Feedback Control as a Framework for Understanding Tradeoffs in Biology

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Date

2014-07-01

Author

Cowan, Noah J.
Ankaralı, Mustafa Mert
Dyhr, Jonathan P.
Madhav, Manu S.
Roth, Eatai
Sefati, Shahin
Sponberg, Simon
Stamper, Sarah A.
Fortune, Eric S.
Daniel, Thomas L.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Control theory arose from a need to control synthetic systems. From regulating steam engines to tuning radios to devices capable of autonomous movement, it provided a formal mathematical basis for understanding the role of feedback in the stability (or change) of dynamical systems. It provides a framework for understanding any system with regulation via feedback, including biological ones such as regulatory gene networks, cellular metabolic systems, sensorimotor dynamics of moving animals, and even ecological or evolutionary dynamics of organisms and populations. Here, we focus on four case studies of the sensorimotor dynamics of animals, each of which involves the application of principles from control theory to probe stability and feedback in an organism's response to perturbations. We use examples from aquatic (two behaviors performed by electric fish), terrestrial (following of walls by cockroaches), and aerial environments (flight control by moths) to highlight how one can use control theory to understand the way feedback mechanisms interact with the physical dynamics of animals to determine their stability and response to sensory inputs and perturbations. Each case study is cast as a control problem with sensory input, neural processing, and motor dynamics, the output of which feeds back to the sensory inputs. Collectively, the interaction of these systems in a closed loop determines the behavior of the entire system.

Subject Keywords

Plant Science, Animal Science and Zoology

URI

https://hdl.handle.net/11511/47971

Journal

INTEGRATIVE AND COMPARATIVE BIOLOGY

DOI

https://doi.org/10.1093/icb/icu050

Collections

Department of Electrical and Electronics Engineering, Article

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Citation Formats

N. J. Cowan et al., “Feedback Control as a Framework for Understanding Tradeoffs in Biology,” INTEGRATIVE AND COMPARATIVE BIOLOGY, pp. 223–237, 2014, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/47971.