Lewis acid catalyzed 1,3-dipolar cycloadditon reactions of stabilized azomethine ylides

Date

2001-01-01

Author

Doğan, Özdemir
KANIŞKAN, Ümit

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Diethylzinc was tested for the first time as the Lewis acid in 1,3-dipolar cycloaddition reactions of azomethine ylides to synthesize pyrrolidine derivatives. A new, easily applicable and highly selective method was developed for the synthesis of highly substituted pyrrolidines. By the application of this method, the synthesis of three new pyrrolidine derivatives was achieved.

Subject Keywords

Cyclo-additions, Diastereofacial selectivity, Proline derivatives, Carbonyl-compounds, Simple generation, 2-amino esters, Amino-acids, Construction, Dipolarophiles, Pyrrolidines

URI

https://hdl.handle.net/11511/53923

Journal

TURKISH JOURNAL OF CHEMISTRY

Collections

Department of Chemistry, Article

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Citation Formats

Ö. Doğan and Ü. KANIŞKAN, “Lewis acid catalyzed 1,3-dipolar cycloadditon reactions of stabilized azomethine ylides,” TURKISH JOURNAL OF CHEMISTRY, pp. 365–371, 2001, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/53923.