CXXC5 is an estrogen responsive gene

Date

2016-09-01

Author

Yasar, P.
Ayaz, G.
Olgun, Çağla Ece
Karakaya, B.
Kars, G.
Muyan, Mesut

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https://hdl.handle.net/11511/54886

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CXXC5 as an unmethylated CpG dinucleotide binding protein contributes to estrogen-mediated cellular proliferation. Ayaz, G; Razizadeh, N; Yaşar, P; Kars, G; Kahraman, Deniz Cansen; Saatci, Ö; Şahin, Ö; Çetin-Atalay, R; Muyan, M (2020-04-06) Evidence suggests that the CXXC type zinc finger (ZF-CXXC) protein 5 (CXXC5) is a critical regulator/integrator of various signaling pathways that include the estrogen (E2)-estrogen receptor α (ERα). Due to its ZF-CXXC domain, CXXC5 is considered to be a member of the ZF-CXXC family, which binds to unmethylated CpG dinucleotides of DNA and through enzymatic activities for DNA methylation and/or chromatin modifications generates a chromatin state critical for gene expressions. Structural/functional features ...
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Citation Formats

P. Yasar, G. Ayaz, Ç. E. Olgun, B. Karakaya, G. Kars, and M. Muyan, “CXXC5 is an estrogen responsive gene,” 2016, vol. 283, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/54886.