Monitoring of Radioprotective Effects of Amifostine on Rat Liver Microsomal Membrane and Brain Tissue Lipids by FTIR Spectroscopy and Microspectroscopy.

Cakmak, G.
Miller, L. M.
Severcan, M.
Zorlu, F.
Severcan, Feride


Evaluation of colloidal platinum on cytotoxicity, oxidative stress and barrier permeability across the gut epithelium
Tuncer, Sinem; Colakoglu, Melis; Ulusan, Sinem; Ertaş, Gülay; KARASU, Çimen; Banerjee, Sreeparna (2019-03-01)
Colloidal platinum (Pt) is widely consumed due to its health promoting benefits. However, the exact biological effects of these nanoparticles have not been studied in detail, particularly in the gut. In the present study we observed that colloidal Pt was not cytotoxic towards three different epithelial colon cancer cell lines. Co-treatment of the colon cancer cell line Caco-2 with the oxidative stress inducing agent hydrogen peroxide (H2O2) and colloidal Pt resulted in a significant decrease in H2O2 induced...
The Structural Investigation of Protective Role of Antiepileptic Vigabatrin in Epilepsy Treatment by FTIR Spectroscopy and Neural Networks
Turker, S.; Severcan, M.; KOMSUOĞLU, SEZER; Severcan, Feride (2011-01-01)
Purification and characterization of two forms of microsomal cytochrome b5 from sheep lung
Basaran, N; Arinc, E (Elsevier BV, 1998-06-01)
Two forms of cytochrome b5 were purified from detergent solubilized sheep lung microsomes by three successive DEAE-cellulose, Sephadex G-100 and Sephadex G-200 column chromatographies. The specific contents of cytochromes b5-I and b5-II were determined to be 45.4 and 43.8 nmol b5/mg protein, which represented up to 567 and 547-fold purification compared with that of the lung microsomes. The most striking difference between b5-I and b5-II was observed in their elution pattern from the third DEAE-cellulose co...
Effects of Commercial Formula Feeding in a Fasting Animal Model: A Fourier Transform Infrared Spectroscopic Study
Dogan, A.; Tuzlaci, A.; Guvenc, B.; Severcan, Feride (2006-01-01)
Simultaneous purification and characterization of cytochrome b5 reductase and cytochrome b5 from sheep liver
Arinc, E; Cakir, D (Elsevier BV, 1999-02-01)
Cytochrome b5 was purified from detergent solubilized sheep liver microsomes by using three successive DEAE-cellulose, and Sephadex G-100 column chromatographies. It was purified 54-fold and the yield was 23.5% with respect to microsomes. The apparent Mr of cytochrome b5 was estimated to be 16,200 +/- 500 by SDS-PAGE. Absolute absorption spectrum of the purified cytochrome b5 showed maximal absorption at 412 nm and dithionite-reduced cytochrome b5 gave peaks at 557, 526.5 and 423 nm. The ability of the puri...
Citation Formats
G. Cakmak, L. M. Miller, M. Severcan, F. Zorlu, and F. Severcan, “Monitoring of Radioprotective Effects of Amifostine on Rat Liver Microsomal Membrane and Brain Tissue Lipids by FTIR Spectroscopy and Microspectroscopy.,” 2011, vol. 22, Accessed: 00, 2020. [Online]. Available: