ALLELE FREQUENCIES OF MP6D-9 AND GATT MARKERS IN 32 TURKISH CYSTIC-FIBROSIS FAMILIES

Date

1994-05-01

Author

OZGUC, M
YILMAZ, E
ERDEM, H
COSKUN, T
OZCELIK, U
Togan, İnci Zehra
GOCMEN, A
AYTER, S
OZALP, I

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The allele frequency of GATT and Mp6D-9 markers was investigated in 32 cystic fibrosis (CF) families. The GATT6 allele was found to be significantly associated with the DELTAF508 mutation. The Mp6D-9 allele 2/GATT6 haplotype was the major haplotype of the mutant alleles. Further analysis of CF alleles for population-specific mutations is underway so that a more direct approach can be taken, especially for families seeking prenatal diagnosis.

Subject Keywords

Genetics(clinical), Genetics

URI

https://hdl.handle.net/11511/57012

Journal

CLINICAL GENETICS

DOI

https://doi.org/10.1111/j.1399-0004.1994.tb04153.x

Collections

Department of Biology, Article

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Citation Formats

M. OZGUC et al., “ALLELE FREQUENCIES OF MP6D-9 AND GATT MARKERS IN 32 TURKISH CYSTIC-FIBROSIS FAMILIES,” CLINICAL GENETICS, pp. 266–268, 1994, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57012.