Enantioselective synthesis of both enantiomers of 2-amino-2-(2-furyl)ethan-1-ol as a flexible building block for the preparation of serine and azasugars

2003-05-16
Demir, Ayhan Sıtkı
Sesenoglu, O
Aksoy-Cam, H
Kaya, H
Aydogan, K
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The selective conversion of 1-(2-furyl)-2-hydroxyethan-1-one and ethyl 2-(2-furyl)-2-oxo acetate into (E)- and (Z)-oximes and oxime ethers followed by oxazaborolidine-catalyzed enantioselective reduction using different amino alcohols furnished both enantiomers of the important chiral building block 2-amino-2-(2-furyl)ethan-1-ol with an ee of up to 96%.
Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Catalysis
https://hdl.handle.net/11511/58036
TETRAHEDRON-ASYMMETRY
Department of Chemistry, Article

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Citation Formats
A. S. Demir, O. Sesenoglu, H. Aksoy-Cam, H. Kaya, and K. Aydogan, “Enantioselective synthesis of both enantiomers of 2-amino-2-(2-furyl)ethan-1-ol as a flexible building block for the preparation of serine and azasugars,” TETRAHEDRON-ASYMMETRY, pp. 1335–1340, 2003, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/58036.
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