RBPSponge: genome-wide identification of lncRNAs that sponge RBPs

Date

2019-11-15

Author

HafezQorani, Saber
Houdjedj, Aissa
Arici, Mehmet
Said, Abdesselam
KAZAN, HİLAL

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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The Summary: Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of interest. Here, we present a web tool named RBPSponge to explore lncRNAs based on their potential to act as a sponge for an RBP of interest. RBPSponge identifies the occurrences of RBP-binding sites and CLIP peaks on lncRNAs, and enables users to run statistical analyses to investigate the regulatory network between lncRNAs, RBPs and targets of RBPs.

Subject Keywords

Statistics and Probability, Computational Theory and Mathematics, Biochemistry, Molecular Biology, Computational Mathematics, Computer Science Applications

URI

https://hdl.handle.net/11511/67904

Collections

Graduate School of Informatics, Article