Interleukin-28 gene polymorphisms may contribute to HBsAg persistence and the development of HBeAg-negative chronic hepatitis B

Date

2015-03-01

Author

Karatayli, Senem C.
Bozdayi, Mithat
Karatayli, Ersin
Ozturk, Tugba
Husseini, Abbas A.
Albayrak, Rabia
Ozkan, Muhip
Kalaylioglu, Zeynep
YALÇIN, KENDAL
Cinar, Kubilay
İDİLMAN, RAMAZAN
Yurdaydin, Cihan

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Background & AimsAim of this study was to investigate whether a potential association exists between several single nucleotide polymorphisms (SNPs) of the IL-28B gene (rs12979860, rs1188122, rs8099917, rs8105790, rs12980275) and HBsAg persistence. Further, a potential effect on the development of HBeAg-negative CHB vs. inactive HBsAg carrier state was assessed in a genotype D HBV cohort. A cohort of chronic HDV patients was also used to see if they behave differently compared to chronic HBV patients.

Subject Keywords

Hepatology

URI

https://hdl.handle.net/11511/68582

Journal

LIVER INTERNATIONAL

DOI

https://doi.org/10.1111/liv.12595

Collections

Department of Statistics, Article

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Citation Formats

S. C. Karatayli et al., “Interleukin-28 gene polymorphisms may contribute to HBsAg persistence and the development of HBeAg-negative chronic hepatitis B,” LIVER INTERNATIONAL, pp. 846–853, 2015, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/68582.