Topical Delivery of Heparin with Polymeric Microparticles

Date

2018-09-08

Author

Akopoğlu, Duygu
Gündüz, Ufuk
Tezcaner, Ayşen
Keskin, Dilek

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https://hdl.handle.net/11511/72859

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Topical Delivery of Heparin with Polymeric Microparticles Akolpoğlu, Duygu; Gündüz, Ufuk; Tezcaner, Ayşen; Keskin, Dilek (null; 2018-09-08)
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Systemic Delivery of Bioactive Glucagon-Like Peptide 1 after Adenoviral-Mediated Gene Transfer in the Murine Salivary Gland Voutetakis, Antonis; Cotrim, Ana P.; Rowzee, Anne; Zheng, Changyu; Rathod, Trushar; Yanık, Tülin; Loh, Y. Peng; Baum, Bruce J.; Cawley, Niamh X. (2010-09-01) Anadenoviral (Ad) vector that expresses bioactive glucagon-like peptide 1 (GLP-1) was generated, and its effectiveness at modulating glucose homeostasis was evaluated after transduction of murine salivary glands. The construct was engineered with the signal sequence of mouse GH to direct the peptide into the secretory pathway, followed by a furin cleavage site and the GLP-1(7-37) sequence encoding an Ala to Gly substitution at position 8 to achieve resistance to degradation. When expressed in Neuro2A and CO...

Citation Formats

D. Akopoğlu, U. Gündüz, A. Tezcaner, and D. Keskin, “Topical Delivery of Heparin with Polymeric Microparticles,” 2018, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/72859.