Modified citrus pectin and silk fibroin based scaffolds for bone tissue engineering applications



Modified acrylic hydrogels as controlled release systems
Pınardağ, Fatma Esra; Hasırcı, Nesrin; Department of Chemistry (2006)
In this study, pH-sensitive poly(acrylamide-co-acrylic acid) hydrogels were synthesized as controlled release systems in the presence of N,N-methylene bisacrylamide as crosslinker and ammonium persulfate as initiator. A set of hydrogels were used in the form they were prepared. One set of hydrogels were prepared as porous networks by incorporating sodium chloride into the reaction medium and then leaching of it after the completion of polymerization reaction. Two sets of hydrogels were modified by argon-pla...
Hybrid metamaterial based structures for the development of a THz spatial light modulator
Chikhi, N.; Casini, R.; Papari, G. P.; Lisitskiy, M.; Tkachenko, V.; Altan, Hakan; Andreone, A. (2014-05-14)
We investigate new classes of artificial materials exhibiting unconventional properties in order to build novel devices operating in the Terahertz regime. The design, fabrication and electromagnetic characterization of tunable meta materials with unit cells based on Split Ring Resonators are presented. By incorporation of a nematic liquid crystal in the structure, we observe a frequency shift in the resonant response over 10% in bandwidth and more than 10 dB change in the signal absorption. We discuss how s...
Modified chitosan scaffolds: Proliferative, cytotoxic, apoptotic, and necrotic effects on Saos-2 cells and antimicrobial effect on Escherichia coli
Ucar, Seniz; Ermiş Şen, Menekşe; Hasırcı, Nesrin (2016-05-01)
Scaffolds used in tissue engineering applications should have high biocompatibility with minimum allergic, toxic, apoptotic, or necrotic effects on the growing cells and newly forming tissue and, if possible, have antimicrobial property to prevent infection at the host site. In this study, novel micro-fibrous chitosan scaffolds, having mineralized bioactive surface to enhance cell adhesion and a model antibiotic (gentamicin) to prevent bacterial attack, were prepared. The effects of the scaffolds on prolife...
Modified Superformula Contours Optimized via Genetic Algorithms for Fastly Converging 2D Solutions of EFIE
Guler, Sadri; Onol, Can; Ergül, Özgür Salih; Hatipoglu, M. Enes; Sever, Emrah; Dikmen, Fatih; Tuchkin, Yury A. (2016-07-01)
It is known that solutions of the integral equations converge at the smoothness rate of the parametrical function representing the boundary contour. Thus using an infinitely smooth parametrical representation with derivatives of all orders results into exponentially converging solutions. A version of superformula tailored for this purpose is exposed to optimization of its parameters via genetic algorithms to obtain smooth parameterization for desired boundaries in two dimensional problems. The convergence o...
Composite clinoptilolite/PCL-PEG-PCL scaffolds for bone regeneration: In vitro and in vivo evaluation
Pazarçeviren, Ahmet Engin; Altunbas, Korhan; Yaprakci, Volkan; Erdemli, Ozge; Keskin, Dilek; Tezcaner, Ayşen (Wiley, 2020-01-01)
In this study, clinoptilolite (CLN) was employed as a reinforcement in a polymer-based composite scaffold in bone tissue engineering and evaluated in vivo for the first time. Highly porous, mechanically stable, and osteogenic CLN/PCL-PEG-PCL (CLN/PCEC) scaffolds were fabricated with modified particulate leaching/compression molding technique with varying CLN contents. We hypothesized that CLN reinforcement in a composite scaffold will improve bone regeneration and promote repair. Therefore, the scaffolds we...
Citation Formats
A. Sibel, D. Keskin, A. Akdağ, and A. Tezcaner, “Modified citrus pectin and silk fibroin based scaffolds for bone tissue engineering applications,” Krakow, Polonya, 2015, p. 653, Accessed: 00, 2021. [Online]. Available: