PCL-Fibrin Scaffolds for Tissue Engineering

2017-05-14

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Scaffolds produced for tissue engineering applications are proven to be promising alternatives to be used in healing and regeneration of injured tissues and organs. In this study, porous and fibrous poly(epsilon-caprolactone) (PCL) scaffolds were prepared by wet spinning technique and modified by addition of tricalcium phosphate (TCP) and by immobilizing gelatin onto fibers. Meanwhile, gelatin microspheres carrying Ceftriaxone sodium (CS), a model antibiotic, were added onto the scaffolds and antimicrobial ...
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Biodegradable polymers have met with an increasing demand in medical usage over the last decades. One of such polymers is poly(epsilon-caprolactone) (PCL), which is a polyester that has been widely used in tissue engineering field for its availability, relatively inexpensive price and suitability for modification. Its chemical and biological properties, physicochemical state, degradability and mechanical strength can be adjusted, and therefore, it can be used under harsh mechanical, physical and chemical co...
Citation Formats
E. Malikmammadov, T. Endoğan Tanır, A. Kızıltay, V. N. Hasırcı, and N. Hasırcı, “PCL-Fibrin Scaffolds for Tissue Engineering,” 2017, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/74984.