Analysis of Glutathione S Transferase 1 GSTO1 ALA140ASP Genetic Polymorphism in Turkish Population

Bilgin, Esra
Can Demirdöğen, Birsen
Demirkaya, Şeref
Adalı, Orhan


Analysis of microsomal epoxide hydrolase tyr113his and his139ARG genotypes with ischemic stroke risk in Turkish population
Micoogullari, Y.; Eroglu, E.; Ozcelik, A. T.; Demirdogen, B. C.; Akgun, H.; Demirkaya, S.; Adalı, Orhan (2011-06-01)
Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population
Demirdogen, Birsen Can; Demirkaya, Seref; Turkanoglu, Aysun; Bek, Semai; Arinc, Emel; Adalı, Orhan (Wiley, 2009-12-01)
Background Paraoxonase 1 (PON1) is protective against the development of atherosclerosis. a risk factor for ischemic stroke. PON1 gene has one promoter region (-107T/C) and two coding region (192Q/R and 55L/M) polymorphisms that affect the levels and catalytic efficiency of the enzyme. respectively. In this study. we aimed to determine the importance of -107T/C. 192Q/R and 55L/M polymorphisms of PON1 gene and three PON1 activity (diazoxonase, paraoxonase, arylesterase) as risk factors for ischemic stroke
Analysis of cytochrome P4501A1 genetic polymorphisms in patients with ischemic stroke
Adalı, Ayşe Çınar; Adalı, Orhan; Demirdöğen, Birsen Can; Department of Biochemistry (2011)
Stroke is the third leading cause of death worldwide and results in serious disabilities. Cytochrome P450 1A1 gene (CYP1A1) is a highly polymorphic gene encoding its corresponding xenobiotic metabolizing enzyme which is responsible from the metabolism of carcinogenic polycyclic aromatic hydrocarbons (PAHs) that are engaged with the formation of free radicals. Atherosclerosis is a major cause of ischemic stroke and this pathology may be associated with the disruption of vascular homeostasis due to the format...
Analysis of immunoreactivity of NOS isoforms (nNOS, eNOS, iNOS) in hippocampus of young rats classified as good and poor learners
Keçecioğlu, Ekin; Jakubowska Doğru, Ewa; Department of Biology (2012)
Despite very extensive studies on molecular mechanisms of learning and memory formation it is little known about individual variation in the learning skills within a random animal population and about the differences in the brain biochemistry behind this variation. In the present study, we have focused on the expression and distribution of nitric oxide synthase (NOS), one of the molecules implemented in activity-dependent neuroplasticity, in the rat hippocampus, the structure critical for episodic memory in...
Analysis of the genetic determinant for production of the pediocin P of Pediococcus pentosaecus Pep 1
Osmanagaoglu, O; Beyatli, Y; Gündüz, Ufuk; Sacilik, SC (2000-01-01)
Pediococcus pentosaceus Pep1 is a vacuum-packaged Turkish sausage isolate which produces a potentially novel bacteriocin of the pediocin (anti-Listeria) family of peptides designated as pediocin P. Curing experiments and plasmid profile analysis indicated that both bacteriocin immunity and production determinants were linked and encoded by 9.0 MDa plasmid, pHD1.0. Attempts to transform purified plasmid pHD1.0 into recipient Escherichia coli JM109 cells by electroporation were successful but none of the E. c...
Citation Formats
E. Bilgin, B. Can Demirdöğen, Ş. Demirkaya, and O. Adalı, “Analysis of Glutathione S Transferase 1 GSTO1 ALA140ASP Genetic Polymorphism in Turkish Population,” 2016, Accessed: 00, 2021. [Online]. Available: