The effects of Phr peptides on the expression of bacABCDE operon in B. subtilis

Date

2008-08-05

Author

Özcengiz, Gülay

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https://hdl.handle.net/11511/87245

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Unverified, Conference / Seminar

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The effects of twelve quorum-sensing gene products on the expression of bacabcde operon in bacillus subtilis Öğülür, İsmail; Özcengiz, Gülay; Department of Biotechnology (2008) In Bacillus subtilis, genetic competence, sporulation and antibiotic production are controlled by quorum-sensing global regulatory mechanism. Bacilysin, being produced and excreted by certain strains of Bacillus subtilis, is a dipeptide antibiotic composed of L-alanine and L-anticapsin. We showed that the biosynthesis of bacilysin is under the control of quorum sensing global regulatory pathway through the action of ComQ/ComX, PhrC (CSF), ComP/ComA in a Spo0K (Opp)-dependent manner. Recently, the ywfBCDEF g...
The effects of insertional mutations in comQ, comP, srfA, spo0H, spo0A and abrB genes on bacilysin biosynthesis in Bacillus subtilis Karatas, AY; Cetin, S; Özcengiz, Gülay (Elsevier BV, 2003-04-15) In Bacillus subtilis, two extracellular signaling peptides, ComX pheromone and CSF (competence and sporulation factor), stimulate the development of genetic competence and surfaction biosynthesis in response to high cell density (quorum sensing) by regulating the activity of transcription factor ComA. We recently showed that biosynthesis of dipeptide antibiotic bacilysin is linked to ComA and PhrC(CSF) in a Spo0K(Opp)-dependent manner by constructing phrC-, comA- and oppA-disrupted mutants of B. subtilis. I...
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Citation Formats

G. Özcengiz, “The effects of Phr peptides on the expression of bacABCDE operon in B. subtilis,” 2008, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/87245.