The Effect of Sin3a Complex on Cell Cycle and Cell Death in Mouse Embryonic Stem Cells

Date

2019-09-29

Author

Güven, Gözde
Terzi Çizmecioğlu, Nihal

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https://hdl.handle.net/11511/79759

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The Effect of SETD3 on Beta-Catenin and Canonical Wnt Signaling Pathway Activity in Mouse Embryonic Stem Cells Alganatay, Ceren; Terzi Çizmecioğlu, Nihal; Department of Molecular Biology and Genetics (2023-1-16) Mouse embryonic stem cells (mESCs) are self-renewing, pluripotent cells that can differentiate into endoderm, mesoderm and neuroectoderm. As differentiation requires deactivation of pluripotency factors and activation of germ layer specific genes, many epigenetic factors play an essential role. A previously performed shRNA screen showed that SETD3 which is a SET-domain containing epigenetic factor, is an essential factor for mesendoderm differentiation of mESCs. Our preliminary data demonstrated that when m...

Citation Formats

G. Güven and N. Terzi Çizmecioğlu, “The Effect of Sin3a Complex on Cell Cycle and Cell Death in Mouse Embryonic Stem Cells,” 2019, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/79759.