Cytotoxic Effect of Kv1.3 Blocker Clofazimine on HCT-116 Colon Cancer Cell Line

3rd EACR-Sponsored Anticancer Agent Development Congress


Cytotoxic Effect of Kv1 3 Blocker Clofazimine on HCT 116 Colon Cancer Cell Line
Husnugil, Hazal; Caner, Yener; Nasit, Igci; Banerjee, Sreeparna; Özen, Can (null; 2015-05-19)
Cytotoxic Effects of Probiotic Bacteria Lactobacillus acidophilus and Lactobacillus rhamnosus Grown in the Presence of Oleuropein on Human Prostate Cancer Cells
Çelebioğlu, Hasan Ufuk; Erden, Yavuz; Evin, Emre; Çelebi, Busenur; Adalı, Orhan (2020-03-01)
Functional foods are groups of foods that have potentially positive effects on health beyond basic nutrition. Probiotics are beneficial microorganisms, being as a group of functional foods, and when ingested in adequate amounts, they possess positive health effects to host organisms including having anti-carcinogenic functions, yet their exact mechanisms how they possess anti-carcinogenic activities are still under investigation. Another group of functional foods is plant-based phenolic compounds. They also...
Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration
Kucukoglu, Kaan; GÜL, Halise İnci; GÜL, Mustafa; Atalay, Rengül; Baratli, Yosra; Geny, Bernard (Bentham Science Publishers Ltd., 2016-01-01)
N,N'-bis[1-(substitutedphenyl)-3-(morpholine-4-yl) propylidene] hydrazine dihydrochlorides, N1-N11 were designed and synthesized as cytotoxic agents. These compounds were synthesized by the reaction of 2 moles of 1-( substitutedphenyl)-3-(morpholine-4-yl)-1-propanone hydrochlorides with 1 mole of hydrazine hydrate. The compounds reported here are new, except N1 and N4. The cytotoxicity of the compounds was tested against human hepatoma (Huh7) and breast cancer (T47D) cell lines. 5-Fluorouracil (5-FU) was us...
Cytotoxicity of some edible mushrooms extracts over liver hepatocellular carcinoma cells in conjunction with their antioxidant and antibacterial properties
SADİ, GÖKHAN; EMSEN, BUĞRAHAN; KAYA, ABDULLAH; KOCABAŞ, AYTAÇ; Cinar, Seval; Kartal, Deniz Irtem (2015-05-01)
Background: Mushrooms have been valued for their nutritive content and as traditional medicines; several important medicinal properties of mushrooms have been recognized worldwide. Objective: The purpose of this study was to elucidate the cell growth inhibitory potential of four edible mushrooms; Coprinus comatus (O.F. Mull.) Pers. (Agaricaceae), Tricholoma fracticum (Britzelm.) Kreisel (Tricholomataceae), Rhizopogon luteolus Fr. and Nordholm (Rhizopogonaceae), Lentinus tigrinus (Bull.) Fr. (Polyporaceae) o...
Cytotoxic and antioxidant activities of three Tanacetum L Taxa from Turkey
Arıtuluk, Zekiye Ceren; Akkulak, Merve; Karakurt, Serdar; Adalı, Orhan; Gençler Özkan, Ayşe Mine (null; 2016-08-25)
Citation Formats
H. H. Hüsnügil, N. İğci, S. Banerjee, and C. Özen, “Cytotoxic Effect of Kv1.3 Blocker Clofazimine on HCT-116 Colon Cancer Cell Line,” presented at the 3rd EACR-Sponsored Anticancer Agent Development Congress, İzmir, Türkiye, 2015, Accessed: 00, 2021. [Online]. Available: