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Cytotoxic Effect of Kv1 3 Blocker Clofazimine on HCT 116 Colon Cancer Cell Line
Date
2015-05-19
Author
Husnugil, Hazal
Caner, Yener
Nasit, Igci
Banerjee, Sreeparna
Özen, Can
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URI
https://hdl.handle.net/11511/86629
Conference Name
3rd EACR-Sponsored Anticancer Agent Development Congress (18 Mayıs 2015 - 19 Mayıs 2014)
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Department of Biology, Conference / Seminar
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Cytotoxic Effect of Kv1.3 Blocker Clofazimine on HCT-116 Colon Cancer Cell Line
Hüsnügil, Hepşen Hazal; İğci, Naşit; Banerjee, Sreeparna; Özen, Can (2015-05-18)
Cytotoxicity of freeze dried EGFR targeted immunoliposome containing celecoxib against overexpressing EGFR and COX-2 colon cancer cell lines and its stability and functional analysis after storage
Banerjee, Sreeparna; Tezcaner, Ayşen(2015-12-31)
In this project, we propose to design EGFR targeted immunoliposome containing celecoxib and use freeze drying as a mean to stabilize it under storage conditions. The mean size, retention of encapsulated materials will be evaluated before lyophilization and after rehydration from storage condition upon its application. In order to show that EGFR antibody of lyophilized immunoliposome maintain its binding activity on the target cell upon rehydration, we will be measuring the extent of immunoliposome internali...
Cytotoxic Effects of Probiotic Bacteria Lactobacillus acidophilus and Lactobacillus rhamnosus Grown in the Presence of Oleuropein on Human Prostate Cancer Cells
Çelebioğlu, Hasan Ufuk; Erden, Yavuz; Evin, Emre; Çelebi, Busenur; Adalı, Orhan (2020-03-01)
Functional foods are groups of foods that have potentially positive effects on health beyond basic nutrition. Probiotics are beneficial microorganisms, being as a group of functional foods, and when ingested in adequate amounts, they possess positive health effects to host organisms including having anti-carcinogenic functions, yet their exact mechanisms how they possess anti-carcinogenic activities are still under investigation. Another group of functional foods is plant-based phenolic compounds. They also...
Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration
Kucukoglu, Kaan; GÜL, Halise İnci; GÜL, Mustafa; Atalay, Rengül; Baratli, Yosra; Geny, Bernard (Bentham Science Publishers Ltd., 2016-01-01)
N,N'-bis[1-(substitutedphenyl)-3-(morpholine-4-yl) propylidene] hydrazine dihydrochlorides, N1-N11 were designed and synthesized as cytotoxic agents. These compounds were synthesized by the reaction of 2 moles of 1-( substitutedphenyl)-3-(morpholine-4-yl)-1-propanone hydrochlorides with 1 mole of hydrazine hydrate. The compounds reported here are new, except N1 and N4. The cytotoxicity of the compounds was tested against human hepatoma (Huh7) and breast cancer (T47D) cell lines. 5-Fluorouracil (5-FU) was us...
Cytotoxicity of some edible mushrooms extracts over liver hepatocellular carcinoma cells in conjunction with their antioxidant and antibacterial properties
SADİ, GÖKHAN; EMSEN, BUĞRAHAN; KAYA, ABDULLAH; KOCABAŞ, AYTAÇ; Cinar, Seval; Kartal, Deniz Irtem (2015-05-01)
Background: Mushrooms have been valued for their nutritive content and as traditional medicines; several important medicinal properties of mushrooms have been recognized worldwide. Objective: The purpose of this study was to elucidate the cell growth inhibitory potential of four edible mushrooms; Coprinus comatus (O.F. Mull.) Pers. (Agaricaceae), Tricholoma fracticum (Britzelm.) Kreisel (Tricholomataceae), Rhizopogon luteolus Fr. and Nordholm (Rhizopogonaceae), Lentinus tigrinus (Bull.) Fr. (Polyporaceae) o...
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H. Husnugil, Y. Caner, I. Nasit, S. Banerjee, and C. Özen, “Cytotoxic Effect of Kv1 3 Blocker Clofazimine on HCT 116 Colon Cancer Cell Line,” presented at the 3rd EACR-Sponsored Anticancer Agent Development Congress (18 Mayıs 2015 - 19 Mayıs 2014), 2015, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/86629.