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Establishment of Human Induced Pluripotent Stem Cells from Multiple Sclerosis Patients
Date
2021-01-01
Author
Kiriş, Erkan
Begentaş, Onur Can
Koç, Dilara
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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URI
https://doi.org/10.1007/7651_2021_453
https://hdl.handle.net/11511/99104
Relation
Methods in Molecular Biology, Induced Pluripotent Stem Cells and Human Disease
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Department of Biology, Book / Book chapter
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Establishment of Human Induced Pluripotent Stem Cells from Multiple Sclerosis Patients.
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The patient-derived iPSC lines provide valuable resources as these cells can be utilized to generate human cell types relevant to the disease of interest. In this context, human iPSC-based model systems are particularly useful for neurological diseases as the neuron and glial cell types affected by such diseases are difficult to obtain. Multiple sclerosis is a demyelinating central nervous system disease characterized by inflammation and eventually axonal damage. iPS cells generated from MS patients may all...
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E. Kiriş, O. C. Begentaş, and D. Koç,
Establishment of Human Induced Pluripotent Stem Cells from Multiple Sclerosis Patients
. 2021.