Parsian, Maryam
Yıldırım, Ender
Ildiz, Can
Özen, Can
The Sixth International Symposium on Pharamceutical and Biomedical Sciences


Development of a microfluidic platform to maintain viability of micro-dissected tumor slices in culture
Parsian, Maryam; MUTLU, PELİN; Yıldırım, Ender; Ildiz, Can; Özen, Can; Gündüz, Ufuk (2022-05-01)
© 2022 Author(s).One of the issues limiting the development of personalized medicine is the absence of realistic models that reflect the nature and complexity of tumor tissues. We described a new tissue culture approach that combines a microfluidic chip with the microdissected breast cancer tumor. "Tumor-on-a-chip"devices are suitable for precision medicine since the viability of tissue samples is maintained during the culture period by continuously feeding fresh media and eliminating metabolic wastes from ...
Development of a novel mixed matrix membrane for pervaporation of ethanol-water mixtures
Cicioğlu, Kezban; Yılmaz, Levent; Department of Chemical Engineering (1993)
Development of a pcr-based specific method for the detection of aspergillus fumigatus by random cdna cloning
Söyler, Alper; Ögel, Zümrüt Begüm; Department of Food Engineering (2004)
Aspergillus fumigatus is a foodborne and airborne human pathogen which produces mycotoxins such as gliotoxin, helvolic acid, fumigallin, and fumigaclavin. The most common disease caused by A. fumigatus is aspergillosis, which is often fatal, especially among AIDS, cancer, and organ-transplant patients. In this study, random cDNA cloning was performed from a cDNA library of A. fumigatus (IMI 385708) constructed on ? ZAP Express. Some of these clones were selected according to their insert sizes and were furt...
Development of a novel functionally graded membrane containing boron-modified bioactive glass nanoparticles for guided bone regeneration
Rad, Reza Moonesi; Atila, Deniz; Evis, Zafer; Keskin, Dilek; Tezcaner, Ayşen (2019-08-01)
Barrier membranes are used in periodontal tissue engineering for successful neo-bone tissue formation and prevention of bacterial colonization. We aimed to prepare and characterize novel 7% boron-modified bioactive glass (7B-BG) containing bilayered membrane for this end. We hypothesized that presence of 7B-BG could promote structural and biological properties of guided bone regeneration (GBR) membrane. Cellulose acetate (CA) layer was prepared by solvent casting, and functionally graded layer of CA/gelatin...
Development of enhanced ultrafiltration methodologies for the resolution of racemic benzoin
Olceroglu, Ayse Hande; Çalık, Pınar; Yılmaz, Levent (Elsevier BV, 2008-09-15)
In the scope of achieving the separation of chiral molecules, enzyme enhanced ultrafiltration (EEUF), a new method based on polymer enhanced ultrafiltration (PEUF), utilizing apoenzymes as ligands, was developed. Benzoin was chosen as the model chiral molecule. Bovine serum albumin (BSA) and apo form of benzaldehyde lyase (BAL) (E.C. were used as chiral ligands in PEUF and EEUF experiments, respectively. In order to bind to the target enantiomer well, the addition of ligand to the benzoin solution...
Citation Formats
M. Parsian, P. MUTLU, E. Yıldırım, C. Ildiz, C. Özen, and U. GÜNDÜZ, “DEVELOPMENT OF A MICROFLUIDIC PLATFORM TO MAINTAIN VIABILITY OF MICRO-DISSECTED TUMOR SLICES IN CULTURE,” presented at the The Sixth International Symposium on Pharamceutical and Biomedical Sciences, Gaziantep, Türkiye, 2022, Accessed: 00, 2022. [Online]. Available: