Transcription factors and target genes involved in plant responses to high boron adaptation

Aksoy, Emre


Transcription level determination of candidate genes upon infections of powdery mildew on barley
Atıcı, Elif; Akkaya, Mahinur S.; Günel, Aslıhan; Department of Biochemistry (2012)
Immune systems are fundamentally based on the differentiation of self and non-self. Unlike mammals, plants have an innate immune system responding to the pathogen only at the site of attack. One of these pathogens is Blumeria graminis f. sp. hordei which is an obligate biotrophic pathogen causing powdery mildew disease and resulting in up to 30% yield loss for both cultivated and wild barley. In this study, Pallas-01 (P-01) and Pallas-03 (P-03) barley lines were inoculated with powdery mildew race Bgh103 (6...
Transcription termination and RNA degradation contribute to silencing of RNA polymerase II transcription within heterochromatin.
Vasiljeva, L; Kim, M; Terzi Çizmecioğlu, Nihal; Soares, LM; Buratowski, S (Elsevier BV, 2008-02-15)
Within the heterochromatin of budding yeast, RNA polymerase II (RNAPII) transcription is repressed by the Sir2 deacetylase. Although heterochromatic silencing is generally thought to be due to limited accessibility of the underlying DNA, there are several reports of RNAPII and basal transcription factors within silenced regions. Analysis of the rDNA array revealed cryptic RNAPII transcription within the "non-transcribed" spacer region. These transcripts are terminated by the Nrd1 /Sen1 complex and degraded ...
Transcriptomic network analysis of brain aging and alzheimers disease
Parvizi, Poorya; Somel, Mehmet; Tunçbağ, Nurcan; Department of Biology (2017)
Multiple studies have investigated aging brain transcriptomes to identify for age-dependent expression changes and determine genes that may participate in age-related dysfunction. However, aging is a highly complex and heterogeneous process where multiple genes contribute at different levels depending on individuals’ environments and genotypes. Both this biological heterogeneity of aging, as well as technical biases and weaknesses inherent to transcriptome measurements, limit the information gained from a s...
Gene expression analysis of drug-resistant MCF-7 cells: implications for relation to extracellular matrix proteins
Iseri, Oezlem Darcansoy; Kars, Meltem Demirel; Arpaci, Fikret; Gündüz, Ufuk (2010-02-01)
Since multidrug resistance is a multifactorial phenomenon, a large-scale expression analysis of drug-resistant cells by using high-density oligonucleotide microarrays may provide information about new candidate genes contributing to resistance. Extracellular matrix (ECM) is responsible for many aspects of proliferation and invasive/metastatic behavior of tumor cells. This study demonstrates alterations in gene expression levels of several ECM components, matrix metalloproteinases (MMPs), adamalysins (ADAMs ...
Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity
Donertas, Handan Melike; İzgi, Hamit; Kamacioglu, Altug; He, Zhisong; Khaitovich, Philipp; Somel, Mehmet (2017-07-19)
It was previously reported that mRNA expression levels in the prefrontal cortex at old age start to resemble pre-adult levels. Such expression reversals could imply loss of cellular identity in the aging brain, and provide a link between aging-related molecular changes and functional decline. Here we analyzed 19 brain transcriptome age-series datasets, comprising 17 diverse brain regions, to investigate the ubiquity and functional properties of expression reversal in the human brain. Across all 19 datasets,...
Citation Formats
E. Aksoy and C. KAYIHAN, Transcription factors and target genes involved in plant responses to high boron adaptation. 2022.