Dönertaş, Eren
Heart-lung machine (HLM) overtakes the functions of the heart and lungs during cardiovascular (open-heart) surgeries. Perfusionists, trained personnel, are in charge of operating, maintaining, and calibrating HLMs. There are some risks associated with cardiovascular surgery due to mistakes made by perfusionists. This creates adverse effects for patients undergoing cardiovascular surgery, operators using the device, and hospital management. In this study, the functions and working principles of HLM, the needs and expectations of perfusionists, and the experience of perfusionists during cardiovascular surgeries are examined in order to determine the points that can be improved with design interventions in various hospitals in Turkey during 2021-2022. The primary aim of the study is to decrease the frequency of human-based errors in the usage of HLM during cardiovascular surgeries by enhancing the perfusionist's experiences. Accordingly, literature review is used to become familiar with HLMs, their context and technical considerations. To understand the requirements and expectations of perfusionists regarding the HLMs, user interviews and surveys are carried out. To analyze how perfusionists engage with one another in a given context and pinpoint areas where perfusionists' experiences could be enhanced, user observations are utilized. The research findings are described in a way that is useful to those working on the design of medical devices, product designers, and design researchers.


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Computational Approaches to Integrated Modeling of Electrophysiology of the Heart
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An accurate understanding of cardiac function necessitates the knowledge of regulation of electromechanical events during a cardiac cycle both on the cellular and organ level. Electrocardiogram (ECG), a recording of the electrical impulses throughout the heart by placing electrodes on specific locations of the body surface, is the most commonly used diagnostic tool measuring the electrical activity of the ventricles and atria through series of waveforms and intervals [1]. ECG is approved to be a key diagnos...
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The heart does not regenerate new functional tissue when myocardium dies following coronary artery occlusion, or if it is defective. Ventricular restoration involves excising the infarct and replacing it with a cardiac patch to restore the heart to a more healthy condition. The goal of this study was to design and develop a clinically applicable myocardial patch to replace myocardial infarcts and improve long-term heart function. A basic design composed of 3D microfibrous mats that house mesenchymal stem ce...
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Citation Formats
E. Dönertaş, “IDENTIFYING POTENTIAL DESIGN INTERVENTIONS FOR HEART-LUNG MACHINES,” M.S. - Master of Science, Middle East Technical University, 2023.