Boron trifluoride catalyzed additions of nucleophiles to endo/exo-2-substituted norbornene derivatives

İşleyen, Alper


Boron trifluoride mediated addition of nucleophiles to endo- and exo-substituted norbornene derivatives
İŞLEYEN, Alper; SAYRAÇ, Tuğmaç; Doğan, Özdemir (2004-01-01)
Remote substituent effects on the regioselectivity and stereoselectivity in the boron trifluoride mediated addition of nucleophiles (iodide and bromide) to endo- and exo-2-substituted norbornene derivatives have been investigated. The main products of the reactions resulted from the regioselective addition of nucleophiles to the double bond of norbornene derivatives. Products resulting from the Wagner-Meerwein type rearrangement were also isolated in considerable amounts. All of the reactions gave the addit...
Boron doped hydroxyapatites in biomedical applications
Uysal, İdil; Yılmaz, Bengi; Evis, Zafer (2020-12-01)
Hydroxyapatite has been widely used in biomedical applications as a coatingmaterial for implant surfaces, a drug carrier, a scaffold or composite for bonetissue engineering applications. The highly ionic structure of hydroxyapatite allowsdoping of various ions, resulting in an improvement in its properties. Boron is oneof the elements which can be doped into hydroxyapatite structure by replacingphosphate (PO43-) or hydroxyl (OH-) sites to obtain scaffolds for bone tissueengineering applications or a coating...
Boron trifluoride mediated Prins reaction of methylene diacetate with styrenes. One-pot synthesis of 3-chloro-3-arylpropanols
İŞLEYEN, ALPER; Doğan, Özdemir (Georg Thieme Verlag KG, 2006-05-03)
A one-pot procedure was developed for the synthesis of 3-chloro-3-arylpropanols, which are important starting materials for the synthesis of biologically active benzanilide derivatives. Styrenes were reacted with methylene diacetate in the presence of boron trifluoride to give the corresponding 3-chloro-3-arylpropanols in 36-84% yield by the Prins reaction. A strongly electron-donating methoxy substituent at either the ortho or para position of the styrene did not give the expected 3-chloro-3-arylpropanols ...
Boron removal from aqueous solutions via polymer enhanced ultrafiltration using novel Imino-bis-propane diol functional polymers
Zerze, Hasan; Özbelge, H. Önder; Yılmaz, Levent; Department of Chemical Engineering (2012)
In this work, newly synthesized poly (vinyl amino-N, N’-bis-propane diol) (GPVA) and copolymer, poly (vinyl amino-N, N’-bis-propane diol-co-DADMAC) (GPVA-co-DADMAC) were efficiently exploited for boron removal via polymer enhanced ultrafiltration (PEUF). Boron concentration could be reduced from 10ppm down to 0.4ppm using GPVA whereas it could be reduced from 10ppm down to 0.8ppm with copolymer GPVA-co-DADMAC at pH 9 and loading (boron-to-polymer mass ratio) 0.001 via continuous polymer enhanced ultrafiltra...
Boron Doped Hydroxyapatite/Tricalcium Phosphate for Bone Tissue Engineering Applications
Pazarçeviren, Ahmet Engin; Keskin, Dilek; Tezcaner, Ayşen; Evis, Zafer (null; 2019-10-20)
Citation Formats
A. İşleyen, “Boron trifluoride catalyzed additions of nucleophiles to endo/exo-2-substituted norbornene derivatives,” Middle East Technical University, 2001.