Boron trifluoride mediated addition of nucleophiles to endo- and exo-substituted norbornene derivatives

SAYRAÇ, Tuğmaç
Doğan, Özdemir
Remote substituent effects on the regioselectivity and stereoselectivity in the boron trifluoride mediated addition of nucleophiles (iodide and bromide) to endo- and exo-2-substituted norbornene derivatives have been investigated. The main products of the reactions resulted from the regioselective addition of nucleophiles to the double bond of norbornene derivatives. Products resulting from the Wagner-Meerwein type rearrangement were also isolated in considerable amounts. All of the reactions gave the addition products in reasonably good yields with high regioselectivity. The endo/exo selectivity, on the other hand, changed depending on the nucleophile and the substrate.


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Ozhava, Derya; Özkar, Saim (Elsevier BV, 2015-09-07)
Rhodium(0) nanoparticles, supported on nanosized hydroxyapatite (Rh(0)/nanoHAP), were prepared by ion exchange of Rh+3 ions with Ca+2 ions of hydroxyapatite, followed by reduction of the resulting Rh+3/nanoHAP precatalyst during the catalytic methanolysis of ammonia borane (AB) in the presence of tetrabutylammonium dihydrogen phosphate (TBAP) at room temperature. Rh(0)/nanoHAP were characterized by a combination of advance analytical techniques including ICP-OES, XRD, TEM, EDX, XPS, ATR-IR and N-2 adsorptio...
Aryl butenoic acid derivatives as a new class of histone deacetylase inhibitors: synthesis, in vitro evaluation, and molecular docking studies
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Demir, Ayhan Sıtkı; Sesenoglu, O; Dunkelmann, P; Muller, M (American Chemical Society (ACS), 2003-06-12)
Benzaldehyde lyase from the Pseudomonas fluorescens catalyzes the reaction of aromatic aldehydes with methoxy and dimethoxy acetaldehyde and furnishes (R)-2-hydroxy-3-methoxy-1-arylpropan-1-one and (R)-2-hydroxy-3,3-dimethoxy-1-arylpropan-1-one in high yields and enantiomeric excess via acyloin linkage. Aromatic aldehydes and benzoins are converted into enamine-carbanion-like intermediates prior to carboligation.
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Herein, we report the in situ generation, isolation and characterization of cobalt(0) nanoparticles, stabilized by poly(4-styrenesulfonic acid-co-maleic acid), PSSMA, and their catalytic activity in the hydrolysis of hydrazine borane (HB). Cobalt(0) nanoparticles having average particle size of 3.1 +/- 0.5 nm were prepared by in situ reduction of cobalt(II) chloride in aqueous solution of hydrazine borane in the presence of PSSMA, isolated magnetically from the catalytic reaction solution using a magnet, an...
Citation Formats
A. İŞLEYEN, T. SAYRAÇ, and Ö. Doğan, “Boron trifluoride mediated addition of nucleophiles to endo- and exo-substituted norbornene derivatives,” ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, pp. 109–118, 2004, Accessed: 00, 2020. [Online]. Available: