Purification and characterization of M2-type kinase isozyme from human meningioma.

Mellati, Ali Awsat


Investigating molecular mechanisms of TRAF7 mutations identified by genome-wide analysis
Gülez, Burcu; Erson Bensan, Ayşe Elif; Günel, Murat; Department of Biotechnology (2017)
Meningiomas are defined as the most common primary intracanial neoplasms which originate from meninges. Recent genomic studies identified critical driver mutations in several genes including TRAF7 (TNF Receptor-Associated Factor 7) . Previously, studies performed in Prof. Gunel’s laboratory suggested that mutant forms of TRAF7 protein were more stable, possibly due to change in their ubiquitination level. To begin understanding the underlying mechanisms, we looked into interaction partners of TRAF7. TRAF7 i...
Synthesis of calcium hydroxyapatite-tricalcium phosphate (HA-TCP) composite bioceramic powders and their sintering behavior
Kivrak, N; Tas, AC (1998-09-01)
Composite (biphasic) mixtures of two of the most important inorganic phases of synthetic bone applications-namely, calcium hydroxyapatite (Ca-10(PO4)(6)(OH)(2) (HA)) and tricalcium phosphate (Ca-3(PO4)(2) (TCP))-were prepared as submicrometer-sized, chemically homogeneous, and high-purity ceramic powders by using a novel, one-step chemical precipitation technique. Starting materials of calcium nitrate tetrahydrate and diammonium hydrogen phosphate salts that were dissolved in appropriate amounts in distille...
Investigation of the brain connectivity disturbance in dyslexic patients
Rasoulzadeh, Vesal; Ulusoy, İlkay; Kalaycıoğlu, Canan; Department of Biomedical Engineering (2016)
Dyslexia is a learning disability that makes reading a challenge, despite normal level of intelligence and receiving adequate instructions. The core deficit in dyslexia is attributed to phonological processing. It’s been suggested that dyslexia is a disconnection syndrome. In this sense, the major sites of phonological processing in the brain are intact and the interconnection between these areas are disturbed. In this study, the disturbance in dyslectic brains based on effective connectivity models in “pre...
Prediction of protein subcellular localization using global protein sequence feature
Bozkurt, Burçin; Atalay, Mehmet Volkan; Department of Computer Engineering (2003)
The problem of identifying genes in eukaryotic genomic sequences by computational methods has attracted considerable research attention in recent years. Many early approaches to the problem focused on prediction of individual functional elements and compositional properties of coding and non coding deoxyribonucleic acid (DNA) in entire eukaryotic gene structures. More recently, a number of approaches has been developed which integrate multiple types of information including structure, function and genetic p...
Identification, characterization and subcellular localization of salt induced proteins in rice (Oryza sativa L.)
Naqvi, Syed Mohammad Saqlan; Yücel, Ayşe Meral; Department of Biology (1993)
Citation Formats
A. A. Mellati, “Purification and characterization of M2-type kinase isozyme from human meningioma.,” Ph.D. - Doctoral Program, Middle East Technical University, 1991.