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Experimental design in the presence of covariates
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143199.pdf
Date
2003
Author
Avcıoğlu, M Didem
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Experimental design methods have broad coverage of application areas. Usually, basic goal in experimental design methods is to compare the effect of controllable experimental factors on the response and locate the interest on the one, which is most effective. However, in many experimental situations, responses are not only affected by the controllable experimental factors, but also by uncontrollable variates, usually named as covariates. Main aim in these models is to relate the response to both the controllable and uncontrollable variates and investigate the effects of the variates on the response. Analysis of covariance (ANCOVA) is a frequently used method of analysis, especially in the biological sciences. Nevertheless, most of the work done on this model is based on the normality assumption of the error distribution. In practice, however, non-normal distributions occur more frequently. The aim of this study is to investigate this model under non-normality and to develop robust and efficient methods for estimation and hypothesis testing.
Subject Keywords
Experimental design
,
Analysis of covariance
,
Maximum Likelihood Estimators (MLE)
,
odified Maximum Likelihood Estimators (MMLE)
,
Robustness
,
Non-normality
URI
https://hdl.handle.net/11511/13638
Collections
Graduate School of Natural and Applied Sciences, Thesis
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M. D. Avcıoğlu, “Experimental design in the presence of covariates,” M.S. - Master of Science, Middle East Technical University, 2003.