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Enantiomeric resolution of racemic tertiary 1-methyl-2-pyrrolylcarbinols by candida cylindracea lipase (CCL)
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093112.pdf
Date
2000
Author
Elmalı, Olcay
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https://hdl.handle.net/11511/2643
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Graduate School of Natural and Applied Sciences, Thesis
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New catalysts have been prepared from (S)- and (R)- proline and the asymmetric borane reduction of prochiral ketones using these catalysts has been studied. The secondary alcohols were obtained in 76-95% yield with 57-96% enantiomeric excesses. Copyright (C) 1996 Elsevier Science Ltd
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O. Elmalı, “Enantiomeric resolution of racemic tertiary 1-methyl-2-pyrrolylcarbinols by candida cylindracea lipase (CCL),” Middle East Technical University, 2000.