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Enantioselective reduction of ketones with borane catalyzed by cyclic β- amino alcohols prepared from proline
Date
1996-12
Author
Demir, Ayhan S
Mecitoglu, Idris
Tanyeli, Cihangir
Gülbeyaz, Volkan
Metadata
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New catalysts have been prepared from (S)- and (R)- proline and the asymmetric borane reduction of prochiral ketones using these catalysts has been studied. The secondary alcohols were obtained in 76-95% yield with 57-96% enantiomeric excesses. Copyright (C) 1996 Elsevier Science Ltd
Subject Keywords
Chirally modified borohydrides
,
Aromatic ketones
,
Achiral ketones
,
Oxazaborolidines
,
Chemistry
,
Reagent
,
Ethers
URI
https://hdl.handle.net/11511/28382
Journal
Tetrahedron: Asymmetry
DOI
https://doi.org/10.1016/s0957-4166(96)00443-0
Collections
Department of Chemistry, Article
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A. S. Demir, I. Mecitoglu, C. Tanyeli, and V. Gülbeyaz, “Enantioselective reduction of ketones with borane catalyzed by cyclic β- amino alcohols prepared from proline,”
Tetrahedron: Asymmetry
, pp. 3359–3364, 1996, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/28382.