Menekşe Ermiş Şen

E-mail

ermism@metu.edu.tr

Department

Center of Excellence in Biomaterials and Tissue Engineering

ORCID

0000-0002-2108-9812

Web of Science Researcher ID

K-5993-2019

Lipopeptide Hydrogel Possesses Adjuvant-Like Properties for the Delivery of the GPC-3 Peptide-derived Antigen Mathes, Tess G.; Kim, Uijin; Jeon, Keuna; Estevez, Paulina Juarez; Terasaki, Miya; Ermiş Şen, Menekşe; O'Raw, Aliesha; Jucaud, Vadim; Khademhosseini, Ali; Falcone, Natashya (2025-01-01) Peptide-based cancer vaccines are attractive as they can elicit antigen-specific cytotoxic T lymphocytes (CTLs) with minimal side effects. However, low immunogenic responses have delayed their translation to the clinic. Ad...
Effects of amyloid-β-mimicking peptide hydrogel matrix on neuronal progenitor cell phenotype Mathes, Tess Grett; Monirizad, Mahsa; Ermiş Şen, Menekşe; de Barros, Natan Roberto; Rodriguez, Marco; Kraatz, Heinz-Bernhard; Jucaud, Vadim; Khademhosseini, Ali; Falcone, Natashya (2024-07-15) Self-assembling peptide-based hydrogels have become a highly attractive scaffold for three-dimensional (3D) in vitro disease modeling as they provide a way to create tunable matrices that can resemble the extracellular mat...
Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications Maity, Surjendu; et. al. (2024-01-01) Glioblastoma (GBM) is an aggressive form of cancer, comprising ≈80% of malignant brain tumors. However, there are no effective treatments for GBM due to its heterogeneity and the presence of the blood-brain barrier (BBB), ...
Gelatin methacryloyl and Laponite bioink for 3D bioprinted organotypic tumor modeling de Barros, Natan Roberto; et. al. (2023-07-20) Three-dimensional (3D)in vitrotumor models that can capture the pathophysiology of human tumors are essential for cancer biology and drug development. However, simulating the tumor microenvironment is still challenging bec...
Nuclear Deformability of Breast Cells Analyzed from Patients with Malignant and Benign Breast Diseases Antmen, Ezgi; Ermiş Şen, Menekşe; Kuren, Ozgur; Beksac, Kemal; Irkkan, Cigdem; HASIRCI, Vasıf Nejat (2023-03-13) Breast cancer is a heterogeneous and dynamic disease, in which cancer cells are highly responsive to alterations in the microenvironment. Today, conventional methods of detecting cancer give a rather static image of the co...
A Cell Culture Chip with Transparent, Micropillar-Decorated Bottom for Live Cell Imaging and Screening of Breast Cancer Cells Ermiş Şen, Menekşe; ANTMEN ALTUNSOY, EZGİ; Kuren, Ozgur; Demirci, Utkan; Hasırcı, Vasıf Nejat (2022-01-01) In the recent years, microfabrication technologies have been widely used in cell biology, tissue engineering, and regenerative medicine studies. Today, the implementation of microfabricated devices in cancer research is fr...
Photo-crosslinked gelatin methacrylate hydrogels with mesenchymal stem cell and endothelial cell spheroids as soft tissue substitutes Ermiş Şen, Menekşe (2021-02-01) Tumors, trauma, and congenital defects require volume restoration of soft tissues. Tissue engineering provides an alternative source for substituting these defects. Cell encapsulation into hydrogels provides a three-dimens...
In situ silver nanoparticle synthesis on 3D-printed polylactic acid scaffolds for biomedical applications ÇALAMAK, SEMİH; Ermiş Şen, Menekşe (2021-02-01) An ultraviolet (UV) irradiation-based in situ silver nanoparticle (AgNP) synthesis approach has drawn significant attention for functionalizing a great variety of biomaterials. Here, we designed an AgNP-functionalized 3D-p...
A Circulating Bioreactor Reprograms Cancer Cells Toward a More Mesenchymal Niche Calamak, Semih; Ermiş Şen, Menekşe; Sun, Han; Islam, Saiful; Sikora, Michael; Nguyen, Michelle; Hasırcı, Vasıf Nejat; Steinmetz, Lars M.; Demirci, Utkan (2020-02-01) Cancer is a complex and heterogeneous disease, and cancer cells dynamically interact with the mechanical microenvironment such as hydrostatic pressure, fluid shear, and interstitial flow. These factors play an essential ro...
Scaffolds for Dermal and Hypodermal Tissue Engineering Can, Funda; Hasırcı, Vasıf Nejat; Tezcaner, Ayşen; Ermiş Şen, Menekşe (2019-10-17)

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