Menekşe Ermiş Şen

Center of Excellence in Biomaterials and Tissue Engineering
Web of Science Researcher ID
A Circulating Bioreactor Reprograms Cancer Cells Toward a More Mesenchymal Niche
Calamak, Semih; Ermiş Şen, Menekşe; Sun, Han; Islam, Saiful; Sikora, Michael; Nguyen, Michelle; Hasırcı, Vasıf Nejat; Steinmetz, Lars M.; Demirci, Utkan (2020-02-01)
Cancer is a complex and heterogeneous disease, and cancer cells dynamically interact with the mechanical microenvironment such as hydrostatic pressure, fluid shear, and interstitial flow. These factors play an essential ro...
Square prism micropillars on poly(methyl methacrylate) surfaces modulate the morphology and differentiation of human dental pulp mesenchymal stem cells
Hasturk, Onur; Ermiş Şen, Menekşe; Demirci, Utkan; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat (2019-06-01)
Use of soluble factors is the most common strategy to induce osteogenic differentiation of mesenchymal stem cells (MSCs) in vitro, but it may raise potential side effects in vivo. The topographies of the substrate surfaces...
Engineered natural and synthetic polymer surfaces induce nuclear deformation in osteosarcoma cells
Antmen Altunsoy, Ezgi; Ermiş Şen, Menekşe; Demirci, Utkan; Hasırcı, Vasıf Nejat (2019-02-01)
Cell-substrate interactions involve constant probing of microenvironment by cells. One of the responses of cells to environmental cues is to change the conformation of their cytoplasm and nucleus. We hypothesized that surf...
Micro and Nanofabrication methods to control cell-substrate interactions and cell behavior: A review from the tissue engineering perspective
Ermiş Şen, Menekşe; Antmen Altunsoy, Ezgi; Hasırcı, Vasıf Nejat (2018-09-01)
Cell-substrate interactions play a crucial role in the design of better biomaterials and integration of implants with the tissues. Adhesion is the binding process of the cells to the substrate through interactions between ...
Modified chitosan scaffolds: Proliferative, cytotoxic, apoptotic, and necrotic effects on Saos-2 cells and antimicrobial effect on Escherichia coli
Ucar, Seniz; Ermiş Şen, Menekşe; Hasırcı, Nesrin (2016-05-01)
Scaffolds used in tissue engineering applications should have high biocompatibility with minimum allergic, toxic, apoptotic, or necrotic effects on the growing cells and newly forming tissue and, if possible, have antimicr...