Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Open Access Guideline
Open Access Guideline
Postgraduate Thesis Guideline
Postgraduate Thesis Guideline
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
Polyurethanes in biomedical applications
Date
2004-01-01
Author
Burke, A
Hasırcı, Nesrin
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
146
views
0
downloads
Cite This
Polyurethanes are the most commonly used materials in the production of blood contacting devices such as heart valves or artificial veins and arteries. They comprise a large family of materials with the only common characteristic of the presence of urethane linkages along the large molecular chains. In general urethane linkages form by the reaction of isocyanates and alcohols. During the preparation and the curing processes of polyurethanes, besides the formation of urethane linkages, many other reactions take place and lead to formation of various bonds such as allophanate, biuret, acylurea or isocyanurate and these bonds may lead to further branching or crosslinking affecting the whole physical, chemical and mechanical properties as well as the biocompatibilities of the resulting polymers
Subject Keywords
Hard segment
,
Blood compatibility
,
Heparin-immobilized polyurethanes
,
Ultrahigh molecular weight polyethylene
,
Soft segment
,
Chain extender
,
Phospholipid polymer
,
Surface modification
,
Poly(urethane urea)
,
Glow-discharge
URI
https://hdl.handle.net/11511/30111
Journal
BIOMATERIALS: FROM MOLECULES TO ENGINEERED TISSUES
DOI
https://doi.org/10.1007/978-0-306-48584-8_7
Collections
Graduate School of Natural and Applied Sciences, Article
Suggestions
OpenMETU
Core
Surface modification of polyurethanes with covalent immobilization of heparin
AKSOY, AYŞEGÜL; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2007-10-04)
Thrombus formation and blood coagulation is a major problem associated with blood contacting products such as catheters, vascular grafts, arteries, artificial hearts and heart valves. An intense research is being conducted towards the synthesis of new hemocompatible materials and modifications of surfaces with biological molecules. In this study, polyurethane (PU) films were synthesized in medical purity from diisocyanate and polyol without using any other ingredients and their surfaces were modified by cov...
Fatigue behavior of Ti-6Al-4V foams processed by magnesium space holder technique
Asik, E. Erkan; Bor, Sakir (2015-01-05)
Porous Ti-6Al-4V alloys are widely used in the biomedical applications for hard tissue implantation due to their elastic moduli being close to that of bone. In this study, porous Ti-6Al-4V alloys were produced with a powder metallurgical process, space holder technique, where magnesium powders were utilized to generate porosity in the range of 51-65 vol%. The production of porous Ti-6Al-4V alloys was composed of three steps. Firstly, spherical Ti-6Al-4V powders with an average size of 55 mu m were mixed wit...
Synthesis and surface modification studies of biomedical polyurethanes to improve long term biocompatibility
Aksoy, Eda Ayşe; Hasırcı, Nesrin; Department of Polymer Science and Technology (2008)
Thrombus formation and blood coagulation is a major problem associated with blood contacting products such as catheters, vascular grafts and artificial hearts. An intense research is being conducted towards the synthesis of new hemocompatible materials and mdifications of surfaces with biological molecules. In this study, polyurethane (PU) films were synthesized in medical purity from diisocyanate and polyol without using any other ingredients and the chemical, thermal and mechanical properties were charact...
Polyethylene oxide-hydroxyapatite composite and microporous polyethylene oxide-polymethacrylic acid polymer complex preparation and characterization
Banat, Raid M I; Tinçer, Teoman; Department of Chemistry (2002)
The first part of this study covers the crosslinking of polyethylene oxide (PEO) and its composite with calcium hydroxyapatite (HA) and their mechanical, swelling and morphological properties. Sheets of neat PEO (two different molecular weights) and composites of PEO-HA were prepared by compression molding. The composites and PEO thick sheets were crosslinked with exposure of UV- irradiation in presence of acetophenone (AP) for different periods of time. This simple method of crosslinking, UV-irradiation in...
Facile control of hydroxyapatite particle morphology by utilization of calcium carbonate templates at room temperature
Oral, Çağatay M.; Çalışkan, Arda; Kapusuz, Derya; Ercan, Batur (Elsevier BV, 2020-09-01)
Hydroxyapatite (HAp, Ca-10(PO4)(6)(OH)(2)) particles are widely used in orthopedic applications due to their chemical resemblance to the inorganic component of bone tissue. Since physical and chemical properties of HAp particles influence bone regeneration, various synthesis techniques were developed to precisely control the particle properties. However, most of these techniques required high reaction temperatures, which limited the spectrum of obtained HAp particle morphologies. In this study, ellipsoidal,...
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
A. Burke and N. Hasırcı, “Polyurethanes in biomedical applications,”
BIOMATERIALS: FROM MOLECULES TO ENGINEERED TISSUES
, pp. 83–101, 2004, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/30111.