Loading of Gemcitabine on chitosan magnetic nanoparticles increases the anti-cancer efficacy of the drug

Date

2016-08-05

Author

PARSIAN, Maryam
UNSOY, Gozde
Mutlu, Pelin
Yalcin, Serap
Tezcaner, Ayşen
Gündüz, Ufuk

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Targeted delivery of anti-cancer drugs increase the efficacy, while decreasing adverse effects. Among various delivery systems, chitosan coated iron oxide nanoparticles (CsMNPs) gained attention with their biocompatibility, biodegradability, low toxicity and targetability under magnetic field. This study aimed to increase the cellular uptake and efficacy of Gemcitabine.

Subject Keywords

Chitosan, Magnetic nanoparticles, Gemcitabine, Targeted drug delivery, Breast cancer

URI

https://hdl.handle.net/11511/31022

Journal

EUROPEAN JOURNAL OF PHARMACOLOGY

DOI

https://doi.org/10.1016/j.ejphar.2016.05.016

Collections

Graduate School of Natural and Applied Sciences, Article

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Citation Formats

M. PARSIAN, G. UNSOY, P. Mutlu, S. Yalcin, A. Tezcaner, and U. Gündüz, “Loading of Gemcitabine on chitosan magnetic nanoparticles increases the anti-cancer efficacy of the drug,” EUROPEAN JOURNAL OF PHARMACOLOGY, pp. 121–128, 2016, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/31022.