Peripheral nerve conduits: Technology update

Date

2014-12-01

Author

Hasırcı, Nesrin
Arslantunalı Şahin, Damla
Dursun Usal, Tuğba
Yücel, Deniz
Hasırcı, Vasıf Nejat

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Peripheral nerve injury is a worldwide clinical problem which could lead to loss of neuronal communication along sensory and motor nerves between the central nervous system (CNS) and the peripheral organs and impairs the quality of life of a patient. The primary requirement for the treatment of complete lesions is a tension-free, end-to-end repair. When end-to-end repair is not possible, peripheral nerve grafts or nerve conduits are used. The limited availability of autografts, and drawbacks of the allografts and xenografts like immunological reactions, forced the researchers to investigate and develop alternative approaches, mainly nerve conduits. In this review, recent information on the various types of conduit materials (made of biological and synthetic polymers) and designs (tubular, fibrous, and matrix type) are being presented.

Subject Keywords

Peripheral nerve injury, Natural biomaterials, Synthetic biomaterials

URI

https://hdl.handle.net/11511/31189

Collections

Graduate School of Natural and Applied Sciences, Article