Development of a Reconstructed Cornea from Collagen-Chondroitin Sulfate Foams and Human Cell Cultures

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Date

2008-12-01

Author

Vrana, N. Engin
Builles, Nicolas
Justin, Virginie
Bednarz, Jurgen
Pellegrini, Graziella
Ferrari, Barbara
Damour, Odile
Hulmes, David J. S.
Hasırcı, Vasıf Nejat

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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PURPOSE. To develop an artificial cornea, the ability to coculture the different cell types present in the cornea is essential. Here the goal was to develop a full-thickness artificial cornea using an optimized collagen-chondroitin sulfate foam, with a thickness close to that of human cornea, by coculturing human corneal epithelial and stromal cells and transfected human endothelial cells.

Subject Keywords

Pigment Epithelial-Cells, In-Vitro, Mechanical-Properties, Nerve Regeneration, Cross-Linking, Stem-Cells, Scaffolds, Keratocytes, Matrix, Substitute

URI

https://hdl.handle.net/11511/31530

Journal

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

DOI

https://doi.org/10.1167/iovs.07-1599

Collections

Graduate School of Natural and Applied Sciences, Article

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Citation Formats

N. E. Vrana et al., “Development of a Reconstructed Cornea from Collagen-Chondroitin Sulfate Foams and Human Cell Cultures,” INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, pp. 5325–5331, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/31530.