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Drug resistant breast cancer cells overexpress ETS1 gene
Date
2010-09-01
Author
Kars, Meltem Demirel
Iseri, Ozlem Darcansoy
Gündüz, Ufuk
Metadata
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Purpose. - Multidrug resistance (MDR) is resistance to wide range of structurally unrelated anticancer agents. MDR is a serious limitation to the effective chemotherapy. Involvement of ETS1 overexpression in upregulation of MDR1 gene expression is implicated. In the present study the aim was to assess the involvement of ETS1 and the genes, which encode the proteins interacting with ETS1 in drug resistant MCF-7 breast cancer cells.
Subject Keywords
ETS1
,
MCF-7
,
MDR1
,
Matrix metalloproteinases
,
Microarray analysis
URI
https://hdl.handle.net/11511/30079
Journal
BIOMEDICINE & PHARMACOTHERAPY
DOI
https://doi.org/10.1016/j.biopha.2010.01.008
Collections
Graduate School of Natural and Applied Sciences, Article
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M. D. Kars, O. D. Iseri, and U. Gündüz, “Drug resistant breast cancer cells overexpress ETS1 gene,”
BIOMEDICINE & PHARMACOTHERAPY
, pp. 458–462, 2010, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/30079.