Drug resistant breast cancer cells overexpress ETS1 gene

Date

2010-09-01

Author

Kars, Meltem Demirel
Iseri, Ozlem Darcansoy
Gündüz, Ufuk

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Purpose. - Multidrug resistance (MDR) is resistance to wide range of structurally unrelated anticancer agents. MDR is a serious limitation to the effective chemotherapy. Involvement of ETS1 overexpression in upregulation of MDR1 gene expression is implicated. In the present study the aim was to assess the involvement of ETS1 and the genes, which encode the proteins interacting with ETS1 in drug resistant MCF-7 breast cancer cells.

Subject Keywords

ETS1, MCF-7, MDR1, Matrix metalloproteinases, Microarray analysis

URI

https://hdl.handle.net/11511/30079

Journal

BIOMEDICINE & PHARMACOTHERAPY

DOI

https://doi.org/10.1016/j.biopha.2010.01.008

Collections

Graduate School of Natural and Applied Sciences, Article

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Citation Formats

M. D. Kars, O. D. Iseri, and U. Gündüz, “Drug resistant breast cancer cells overexpress ETS1 gene,” BIOMEDICINE & PHARMACOTHERAPY, pp. 458–462, 2010, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/30079.