Epidermal growth factor-containing wound closure enhances wound healing in non-diabetic and diabetic rats

Dogan, S.
Kepenekci, I.
Erkek, B.
Kızıltay, Aysel
Hasırcı, Nesrin
Nazikoglu, A.
Renda, N.
Dincer, U. D.
Kuterdem, E.
Background: This study was designed to elucidate the in vivo efficacy of epidermal growth factor (EGF) on wound healing in non diabetic and diabetic rats.


Electrophysiologic vestibular evaluation in type 2 diabetic and prediabetic patients: Air conduction ocular and cervical vestibular evoked myogenic potentials
Konukseven, Ozlem; Polat, Sefi Ka Burcak; KARAHAN, SEVİLAY; Konukseven, Erhan İlhan; Ersoy, Reyhan; Cakir, Bekir; Kutluhan, Ahmet; AKSOY, SONGÜL (2015-01-01)
Objective: Chronically increased blood glucose levels may affect the vestibular system by damaging cells and neural structures in diabetes mellitus (DM). We aimed to search the effects of neurovascular degeneration on the vestibular system in type 2 DM and prediabetic patients by using air-conducted ocular (oVEMP) and cervical (cVEMP) vestibular evoked myogenic potentials. Design: Prospective study. Study sample: Thirty diabetic, 30 prediabetic patients, and 31 age-and sex-matched controls having no periphe...
Gelatin Based Scaffolds and Effect of EGF Dose on Wound Healing
Bilgic, H.; Demiriz, M.; Ozler, M.; Ide, Tayfun; Dogan, N.; Gumus, S.; Kızıltay, Aysel; Endoğan Tanır, Tuğba; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2013-04-01)
In this study, gelatin based biodegradable scaffolds (GS) containing various amounts of epidermal growth factor (EGF) were prepared and applied to full skin defects created on rats in order to investigate the EGF dose effect on healing process. Scaffolds were prepared by freeze drying technique and stabilized with either glutaraldehyde (GA) or 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDAC). In vitro cytotoxicity of the prepared scaffolds was assessed by using human skin fibroblast secondary culture (...
Validity and reliability of time management questionnaire
ALAY, SEMA; Koçak, Mehmet Settar (SAGE Publications, 2002-01-01)
the purpose of this study was to test the psychometric properties of the 49-item Diabetes Time Management Questionnaire (DTMQ) in individuals with diabetes. The (DTMQ) was designed to assess general time management skills and those specifically relevant to compliance to a diabetes healthcare regimen.
Sustained local application of low-dose epidermal growth factor on steroid-inhibited colonic wound healing
Sakallioglu, AE; Yagmurlu, A; Dindar, H; Hasırcı, Nesrin; Renda, N; Deveci, MS (2004-04-01)
Background/Purpose: The effects of locally administered low-dose epidermal growth factor in a steroid-inhibited wound healing were investigated in a rat model.
Structural effects of simvastatin on liver rate tissue: Fourier transform infrared and Raman microspectroscopic studies
Garip, Sebnem; Bayari, Sevgi Haman; Severcan, Mete; Abbas, Sherif; Lednev, Igor K.; Severcan, Feride (2016-02-01)
Simvastatin is one of the most frequently prescribed statins because of its efficacy in the treatment of hypercholesterolemia, reducing cardiovascular risk and related mortality. Determination of its side effects on different tissues is mandatory to improve safe use of this drug. In the present study, the effects of simvastatin on molecular composition and structure of healthy rat livers were investigated by Fourier transform infrared and Raman imaging. Simvastatin-treated groups received 50 mg/kg/day simva...
Citation Formats
S. Dogan et al., “Epidermal growth factor-containing wound closure enhances wound healing in non-diabetic and diabetic rats,” INTERNATIONAL WOUND JOURNAL, pp. 107–115, 2009, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/32647.