Antimicrobial aptamers for detection and inhibition of microbial pathogen growth

Date

2013-03-01

Author

Ozalp, Veli Cengiz
Bilecen, Kivanc
Kavruk, Murat
Öktem, Hüseyin Avni

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Discovery of alternative sources of antimicrobial agents are essential in the ongoing battle against microbial pathogens. Legislative and scientific challenges considerably hinder the discovery and use of new antimicrobial drugs, and new approaches are in urgent demand. On the other hand, rapid, specific and sensitive detection of airborne pathogens is becoming increasingly critical for public health. In this respect affinity oligonucleotides, aptamers, provide unique opportunities for the development of nanotechnological solutions for such medical applications. In recent years, aptamers specifically recognizing microbial cells and viruses showed great potential in a range of analytical and therapeutic applications. This article describes the significant advances in the development of aptamers targeting specific pathogens. Therapeutic application of aptamers as neutralizing agents demonstrates great potential as a future source of antimicrobial agent.

Subject Keywords

Microbiology (medical), Microbiology

URI

https://hdl.handle.net/11511/34819

Journal

FUTURE MICROBIOLOGY

DOI

https://doi.org/10.2217/fmb.12.149

Collections

Department of Biology, Article

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Citation Formats

V. C. Ozalp, K. Bilecen, M. Kavruk, and H. A. Öktem, “Antimicrobial aptamers for detection and inhibition of microbial pathogen growth,” FUTURE MICROBIOLOGY, pp. 387–401, 2013, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/34819.