Auxiliary mediated synthesis of aziridine 2 carboxylic acid derivative

Date

1994-03-01

Author

GARNER, Philip
Doğan, Özdemir
PİLLAİ, Satish

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

188
views

0
downloads

A convenient protocol for the asymmetric synthesis of stereodefined aziridine-2-carboxylic acid derivatives from alpha,beta-unsaturated acryloyl- and crotonoyl camphor sultams is reported.

Subject Keywords

Ring-opening reactions, Amino-acids, 2-aziridinecarboxylic acid, Esters, Aziridines, Mitomycins, Reagents

URI

https://hdl.handle.net/11511/34858

Journal

Tetrahedron Letters

DOI

https://doi.org/10.1016/0040-4039(94)88311-4

Collections

Department of Chemistry, Article

Suggestions

OpenMETU
Core

Direct hydrothermal synthesis of palladium-incorporated silicate-structured mesoporous catalysts Sener, Canan; Doğu, Timur; Dogu, Guelsen (2007-01-01) Pd-Si-structured novel mesoporous nanocomposite catalytic materials, having quite high Pd/Si ratios, were synthesized by an acidic direct hydrothermal synthesis route. The nanocomposite catalytic materials were then characterized by XRD, XPS, EDS, nitrogen adsorption, and SEM techniques. Unlike MCM-41, the XRD patterns indicated a rather wide d((100)) band at a 2 theta value of about 1.9. The materials, with very high Pd/Si wt ratios between 1.43 and 2.66, were synthesized and had BJH surface area values be...
Diethylzinc mediated 1 3 dipolar cycloaddition reaction of chiral azomethine ylides asymmetric synthesis of ferrocenyl substituted pyrrolidine derivatives Doğan, Özdemir; DİNÇER, Ülkü; ARICI, Cengiz (2002-10-01) Asymmetric synthesis of ferrocenyl-substituted pyrrolidine derivatives was successfully achieved by diethylzinc-mediated 1,3-dipolar cycloaddition reactions of chiral azomethine ylides with a number of electron-deficient dipolarophiles. Chiral azomethine ylides were formed by condensing glycyl sultam with ferrocenecarboxaldehyde via imine tautomerization and complexation with diethylzinc. All of the cycloaddition reactions gave ferrocenyl-substituted pyrrolidine derivatives with very high regio- and diaster...
Immobilization of dioxomolybdenum(VI) complex bearing salicylidene 2-picoloyl hydrazone on chloropropyl functionalized SBA-15: A highly active, selective and reusable catalyst in olefin epoxidation Bagherzadeh, Mojtaba; Zare, Maryam; Salemnoush, Taghi; Özkar, Saim; Akbayrak, Serdar (Elsevier BV, 2014-04-05) A novel organic-inorganic hybrid heterogeneous catalyst system was obtained from the reaction of the molybdenum(VI) complex of salicylidene 2-picoloyl hydrazone with mesoporous silica containing 3-chloropropyl groups prepared by a direct synthetic approach involving hydrolysis and co-condensation of tetraethylorthosilicate (TEOS) and 3-chloropropyltrimethoxysilane in the presence of the triblock copolymer P123 as template under acidic conditions. Characterization of the functionalized materials by X-ray dif...
Activated carbon-tungstophosphoric acid catalysts for the synthesis of tert-amyl ethyl ether (TAEE) Obali, Zeynep; Doğu, Timur (2008-05-01) Catalytic activities of bulk tungstophosphoric acid (HPW) and its supported forms on activated carbon were investigated in the vapor phase etherification reaction of isoamylene with ethanol in a continuous flow reactor. Tungstophosphoric acid (H3PW12O40 center dot 11H(2)O) was supported on activated carbon having a surface area of 796 m(2)/g, at two different loading levels (25% and 31%) by aqueous impregnation technique and the kinetic experiments were done in a temperature range between 353 and 370 K. Sup...
Asymmetric organocatalytic direct Mannich reaction of acetylacetone and isatin derived ketimines: Low catalyst loading in chiral cinchona-squaramides İŞİBOL, Duygu; Karahan, SEDA; Tanyeli, Cihangir (2018-02-07) A highly enantioselective synthesis of 3-amino-2-oxindoles by direct Mannich reaction between acetylacetone and N-carbamoyl isatin ketimine has been described herein. Corresponding chiral adducts were obtained in high yields (up to 98%) and with excellent enantioselectivities (up to >99% ee) by very low (1 mol%) catalyst loading of 2-adamantyl substituted bifunctional cinchona-squaramide.

Citation Formats

P. GARNER, Ö. Doğan, and S. PİLLAİ, “Auxiliary mediated synthesis of aziridine 2 carboxylic acid derivative,” Tetrahedron Letters, pp. 1653–1656, 1994, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/34858.