Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa

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10.11861471-2164-15-963.pdf

Date

2014-11-07

Author

Alkan, Can
Kavak, Pinar
Somel, Mehmet
Gokcumen, Omer
Ugurlu, Serkan
Saygi, Ceren
Dal, Elif
Bugra, Kuyas
GÜNGÖR, TUNGA
Sahinalp, S. Cenk
ÖZÖREN, NESRİN
BEKPEN, CEMALETTİN

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Background: Turkey is a crossroads of major population movements throughout history and has been a hotspot of cultural interactions. Several studies have investigated the complex population history of Turkey through a limited set of genetic markers. However, to date, there have been no studies to assess the genetic variation at the whole genome level using whole genome sequencing. Here, we present whole genome sequences of 16 Turkish individuals resequenced at high coverage (32 x -48x).

Subject Keywords

Population-Structure, Wide Association, Skin Pigmentation, Diversity, Origin, DNA, Discovery, Inversion, Haplotype, Architecture

URI

https://hdl.handle.net/11511/36597

Journal

BMC GENOMICS

DOI

https://doi.org/10.1186/1471-2164-15-963

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Department of Biology, Article

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Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa Gokcumen, Omer; Alkan, Can; Kavak, Pinar; Somel, Mehmet; Ugurlu, Serkan; Dal, Elif; Bugra-Bilge, Kuyas; Gungor, Tunga; Sahinalp, Cenk; Ozeren, Nesrin; Bekpen, Cemalettin (2014-03-01) Background: Turkey is a crossroads of major population movements throughout history and has been a hotspot of cultural interactions. Several studies have investigated the complex population history of Turkey through a limited set of genetic markers. However, to date, there have been no studies to assess the genetic variation at the whole genome level using whole genome sequencing. Here, we present whole genome sequences of 16 Turkish individuals resequenced at high coverage (32 × −48×). Results: We show tha...
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Citation Formats

C. Alkan et al., “Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa,” BMC GENOMICS, pp. 0–0, 2014, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/36597.