Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series

Yuan, Yuan
Chen, Yi-Ping Phoebe
Ni, Shengyu
Xu, Augix Guohua
Tang, Lin
Vingron, Martin
Somel, Mehmet
Khaitovich, Philipp
Background: Comparing biological time series data across different conditions, or different specimens, is a common but still challenging task. Algorithms aligning two time series represent a valuable tool for such comparisons. While many powerful computation tools for time series alignment have been developed, they do not provide significance estimates for time shift measurements.