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Discovering functional interaction patterns in protein-protein interaction networks
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Date
2008-06-11
Author
Turanalp, Mehmet E.
Can, Tolga
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This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of genes and/or proteins of an increasing number of organisms. A protein-protein interaction (PPI) network is a particular biological network which represents physical interactions between pairs of proteins of an organism. Major research on PPI networks has focused on understanding the topological organization of PPI networks, evolution of PPI networks and identification of conserved subnetworks across different species, discovery of modules of interaction, use of PPI networks for functional annotation of uncharacterized proteins, and improvement of the accuracy of currently available networks.
Subject Keywords
Biochemistry
,
Applied Mathematics
,
Molecular Biology
,
Structural Biology
,
Computer Science Applications
URI
https://hdl.handle.net/11511/47646
Journal
BMC BIOINFORMATICS
DOI
https://doi.org/10.1186/1471-2105-9-276
Collections
Department of Computer Engineering, Article