Carboligation reactions with benzaldehyde lyase immobilized on superparamagnetic solid support

Date

2009-01-01

Author

Sopaci, S. Betuel
Turan, Ilke Simsek
Tural, Bilsen
Volkan, Mürvet
Demir, Ayhan Sıtkı

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Histidine-tagged recombinant benzaldehyde lyase (BAL, EC 4.1.2.38) was efficiently immobilized to surface-modified magnetic particles with affinity ligand binding. In addition to conventional benzoin condensation reactions, two important representative BAL-catalyzed carboligation reactions, were also performed with this magnetically responsive biocatalyst. The results obtained from the carboligation reactions that were performed with this simple and convenient heterogenous biocatalyst were comparable to that of free-enzyme-catalyzed reactions.

Subject Keywords

Physical and Theoretical Chemistry, Organic Chemistry, Biochemistry

URI

https://hdl.handle.net/11511/36935

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY

DOI

https://doi.org/10.1039/b819722a

Collections

Department of Chemistry, Article

Citation Formats

S. B. Sopaci, I. S. Turan, B. Tural, M. Volkan, and A. S. Demir, “Carboligation reactions with benzaldehyde lyase immobilized on superparamagnetic solid support,” ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 7, no. 8, pp. 1658–1664, 2009, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/36935.