INTERINDIVIDUAL VARIABILITY OF COUMARIN 7-HYDROXYLATION IN A TURKISH POPULATION

1994-11-01
ISCAN, M
ROSTAMI, H
ISCAN, M
Güray, Nülüfer Tülün
PELKONEN, O
RAUTIO, A
One hundred healthy Turkish Volunteers (70 male, 30 female) aged from 19 to 56 years were given 5 mg coumarin p.o. after an overnight fast. Urine samples were collected before and 2, 4 and 8 h after drug administration. The extent and rate of formation of 7-OH-coumarin (7OHC) was determined by the urinary excretion of the metabolite as measured with the fluorometric method.

Citation Formats
M. ISCAN, H. ROSTAMI, M. ISCAN, N. T. Güray, O. PELKONEN, and A. RAUTIO, “INTERINDIVIDUAL VARIABILITY OF COUMARIN 7-HYDROXYLATION IN A TURKISH POPULATION,” EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, vol. 47, no. 4, pp. 315–318, 1994, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/37689.