Conformational control on remote stereochemistry in the intramolecular Pauson-Khand reactions of enynes tethered to homoallyl and homopropargyl alcohols

2006-11-17
Sezer, Serdar
Ozdemirhan, Devrim
Sahin, Ertan
Tanyeli, Cihangir
An intramolecular Pauson-Khand reaction of enynes derived from homoallyl and homopropargyl alcohols is described. 2-Furyl substituted homoallyl and homopropargyl alcohols are easily and efficiently resolved through enzymatic resolution in a high ee (93-99%) with a known stereochemistry. Each enantiomerically enriched enyne affords the conformationally most stable diastereomeric cyclopenta[c]pyran ring system.

Citation Formats
S. Sezer, D. Ozdemirhan, E. Sahin, and C. Tanyeli, “Conformational control on remote stereochemistry in the intramolecular Pauson-Khand reactions of enynes tethered to homoallyl and homopropargyl alcohols,” TETRAHEDRON-ASYMMETRY, vol. 17, no. 21, pp. 2981–2986, 2006, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/40073.