Conformational control on remote stereochemistry in the intramolecular Pauson-Khand reactions of enynes tethered to homoallyl and homopropargyl alcohols

Date

2006-11-17

Author

Sezer, Serdar
Ozdemirhan, Devrim
Sahin, Ertan
Tanyeli, Cihangir

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An intramolecular Pauson-Khand reaction of enynes derived from homoallyl and homopropargyl alcohols is described. 2-Furyl substituted homoallyl and homopropargyl alcohols are easily and efficiently resolved through enzymatic resolution in a high ee (93-99%) with a known stereochemistry. Each enantiomerically enriched enyne affords the conformationally most stable diastereomeric cyclopenta[c]pyran ring system.

Subject Keywords

Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Catalysis

URI

https://hdl.handle.net/11511/40073

Journal

TETRAHEDRON-ASYMMETRY

DOI

https://doi.org/10.1016/j.tetasy.2006.11.012

Collections

Department of Chemistry, Article

Citation Formats

S. Sezer, D. Ozdemirhan, E. Sahin, and C. Tanyeli, “Conformational control on remote stereochemistry in the intramolecular Pauson-Khand reactions of enynes tethered to homoallyl and homopropargyl alcohols,” TETRAHEDRON-ASYMMETRY, vol. 17, no. 21, pp. 2981–2986, 2006, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/40073.