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Alteration of enzyme activities and kinetic properties of GST and NQO1 with naturally occurring phenolic compounds

Sever, Melike
Celebioglu, Hasan Ufuk
Adalı, Orhan
Objective: Glutathione S-transferase (GST) and NAD(P)H:quinine oxidoreductase 1 (NQO1) are the enzymes important in cytoprotection and bioactivation of chemicals. This study has addressed effects of polyphenolic compounds; ellagic acid, quercetin, naringenin, resveratrol, rutin and hesperidin on rabbit liver GST and NQO1 enzyme activities.