The-137G/C Polymorphism in Interleukin-18 Gene Promoter Contributes to Chronic Lymphocytic and Chronic Myelogenous Leukemia Risk in Turkish Patients

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10.4274:tjh.2014.0126.pdf

Date

2015-01-01

Author

Yalcin, Serap
Mutlu, Pelin
Cetin, Turker
Sarper, Meral
Ozgur, Gokhan
Avcu, Ferit

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Objective: Interleuldn-18 (IL-18) is a cytokine that belongs to the IL-1 superfamily and is secreted by various immune and nonimmune cells. Evidence has shown that 1L-18 has both anticancer and procancer effects. The aim of this study was to evaluate the relationship between IL-18 gene polymorphisms and susceptibility to chronic lymphocytic leukemias (CLL) and chronic myelogenous leukemias (CML) in Turkish patients.

Subject Keywords

Chronic lymphocytic leukemia, Chronic myelogenous leukemia, Single nucleotide polymorphisms, IL-18

URI

https://hdl.handle.net/11511/41831

Journal

TURKISH JOURNAL OF HEMATOLOGY

DOI

https://doi.org/10.4274/tjh.2014.0126

Collections

Test and Measurement Center In advanced Technologies (MERKEZ LABORATUVARI), Article

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Citation Formats

S. Yalcin, P. Mutlu, T. Cetin, M. Sarper, G. Ozgur, and F. Avcu, “The-137G/C Polymorphism in Interleukin-18 Gene Promoter Contributes to Chronic Lymphocytic and Chronic Myelogenous Leukemia Risk in Turkish Patients,” TURKISH JOURNAL OF HEMATOLOGY, pp. 311–316, 2015, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/41831.